Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH4 | Q9H3N8 | 14/20 | 0.63 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.63 |
| ▸ | HRH2 | P25021 | 1/20 | 0.63 |
| ▸ | DNM2 | P50570 | 2/20 | 0.43 |
| ▸ | FLT3 | P36888 | 1/20 | 0.43 |
| ▸ | TYRO3 | Q06418 | 1/20 | 0.43 |
| ▸ | MERTK | Q12866 | 1/20 | 0.43 |
| ▸ | GAS6 | Q14393 | 1/20 | 0.43 |
| ▸ | KDR | P35968 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1774487 | 0.77 | HRH4 (0.72) | HRH4HRH3HRH2KDR | |
| SCHEMBL1774550 | 0.77 | HRH4 (1.00) | HRH4HRH3HRH2KDR | |
| SCHEMBL18636724 | 0.76 | HRH4 (0.50) | HRH4HRH3HRH2FLT3KDR | |
| SCHEMBL1776779 | 0.76 | HRH4 (0.79) | HRH4HRH3HRH2KDR | |
| SCHEMBL1775524 | 0.75 | HRH4 (0.67) | HRH4HRH3 | |
| SCHEMBL1773934 | 0.75 | HRH4 (0.68) | HRH4HRH3HRH2KDR | |
| SCHEMBL1774562 | 0.75 | HRH4 (0.68) | HRH4HRH3HRH2KDR | |
| SCHEMBL4752569 | 0.74 | HRH4 (0.70) | HRH4HRH3HRH2KDR | |
| SCHEMBL1775001 | 0.71 | HRH4 (1.00) | HRH4HRH3HRH2KDR | |
| SCHEMBL1774691 | 0.71 | HRH4 (0.67) | HRH4HRH3HRH2KDR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1966162-B1 | PYRIMIDINE DERIVATIVES | ZIARCO PHARMA LTD (GB) | 2017-03-15 | — | — | EP | disclosed |