SCHEMBL186381

SCHEMBL186381

O=[N+]([O-])n1cnc2ccccc21

nearest known ligand 0.53

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.49
FGFR1 P11362 2/20 0.49
GAA P10253 1/20 0.48
HTT P42858 4/20 0.47
TDP1 Q9NUW8 1/20 0.46
MAPT P10636 2/20 0.44
KDM4E B2RXH2 1/20 0.44
NPSR1 Q6W5P4 1/20 0.44
MEN1 O00255 3/20 0.43
KMT2A Q03164 3/20 0.43
MITF O75030 1/20 0.43
SMN1; SMN2 Q16637 1/20 0.43
ALOX5 P09917 1/20 0.42
ALDH3A1 P30838 3/20 0.41
POLB P06746 1/20 0.41
NOD1 Q9Y239 1/20 0.41
L3MBTL1 Q9Y468 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Iodide SCHEMBL11500379 0.98 ALDH1A1 (0.48) ALDH1A1FGFR1GAAHTTTDP1
SCHEMBL11508815 0.98 ALDH1A1 (0.48) ALDH1A1FGFR1GAAHTTTDP1
SCHEMBL4258614 0.73 ALDH1A1 (0.46) ALDH1A1FGFR1GAAHTTTDP1
SCHEMBL30522768 0.69 CDK4 (0.43) ALDH1A1HTTMEN1KMT2AL3MBTL1
SCHEMBL4080987 0.69 CDK4 (0.43) ALDH1A1HTTMEN1KMT2AL3MBTL1
SCHEMBL6298248 0.69 ALDH1A1 (0.72) ALDH1A1FGFR1GAAHTTMAPT
SCHEMBL3834819 0.69 FGFR1 (0.72) ALDH1A1FGFR1HTTMAPT
SCHEMBL14879323 0.69 DAO (0.38) ALDH1A1MAPTKDM4ENPSR1MEN1
SCHEMBL3673037 0.69 TDP1 (0.54) FGFR1HTTTDP1MEN1KMT2A
SCHEMBL19350754 0.68 FGFR1 (0.62) ALDH1A1FGFR1HTTMAPTKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 2529 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250277257-A1 HYBRIDIZATION COMPOSITIONS AND METHODS DAKO DENMARK APS (DK) 2025-09-04 US claimed
CN-119638632-A Nitro-imidazole and amino preparation method of benzimidazole compound 烟台海川化学制品有限公司 2025-03-18 CN claimed
CN-118619886-B Bisbenzimidazole phenoxy alkyl diamine compound and preparation method and application thereof 山东齐氟新材料有限公司 2024-10-25 CN claimed
CN-118652479-A Degradable antibacterial hydrogel and preparation method thereof 江苏欧亚立日化有限公司 2024-09-17 CN claimed
CN-118619886-A Bisbenzimidazole phenoxy alkyl diamine compound and preparation method and application thereof 山东齐氟新材料有限公司 2024-09-10 CN claimed
CN-117534620-A Preparation method of palladium-catalyzed hydrocarbon bond functionalized 2-trifluoromethyl benzimidazole compound 六盘水师范学院 2024-02-09 CN claimed
CN-109988794-B Method for synthesizing nitrobenzimidazole derivatives through enzyme catalysis in continuous flow reactor 浙江农林大学 2023-06-13 CN claimed
US-20230123029-A1 ZIF NANOPARTICLE CONTAINING TRI-LIGANDS, THE METHOD OF MANUFACTURING THE SAME, MIXED MATRIX MEMBRANE COMPRISING THE SAME AND METHOD OF SEPARATING GAS USING THE MEMBRANE SOGANG UNIVERSITY RESEARCH & BUSINESS DEVELOPMENT FOUNDATION (KR) 2023-04-20 US claimed
CN-115128195-A LC-MS/MS detection method for pesticide and veterinary drug residues in animal oil and vegetable oil 北京市疾病预防控制中心 2022-09-30 CN claimed
US-20220162683-A1 COMPOSITIONS AND METHODS FOR PERFORMING HYBRIDIZATIONS WITH NO DENATURATION DAKO DENMARK APS (DK) 2022-05-26 US claimed
WO-2003050306-A1 HYBRIDIZATION PORTION CONTROL OLIGONUCLEOTIDE AND ITS USES SEEGENE, INC. (KR) 2003-06-19 WO claimed
WO-2003050305-A1 ANNEALING CONTROL PRIMER AND ITS USES SEEGENE, INC. (KR) 2003-06-19 WO claimed
EP-0670053-A1 SOLID ANTIFOGGANT AGENT AND SOLID SINGLE PART HIGH CONTRAST RAPID ACCESS DEVELOPER SUN CHEMICAL CORPORATION (US) 1995-09-06 EP claimed
WO-1994011783-A1 SOLID ANTIFOGGANT AGENT AND SOLID SINGLE PART HIGH CONTRAST RAPID ACCESS DEVELOPER SUN CHEMICAL CORPORATION (US) 1994-05-26 WO claimed
US-5272045-A Water soluble antifoggant for powder developer solutions SUN CHEMICAL CORPORATION (US) 1993-12-21 US claimed
EP-0448841-B1 PHOTOGRAPHIC MATERIALS CONTAINING ELECTRON ACCEPTING AGENTS AGFA-GEVAERT N.V. (BE) 1993-06-02 EP claimed
US-5198333-A Nitro-containing heterocyclic compoudns; positive or negative roomlight emulsions; graphic arts AGFA-GEVAERT, N.V. (BE) 1993-03-30 US claimed
EP-0448841-A1 Photographic materials containing electron accepting agents AGFA-GEVAERT N.V. (BE) 1991-10-02 EP claimed
US-4469780-A COMBINED DEVELOPMENT AND INTENSIFICATION BATH FUJI PHOTO FILM CO., LTD. (JP) 1984-09-04 US claimed
US-4121938-A Photographic material containing TiO2, soluble Cu(II) salt, and soluble silver salt and the use thereof in physical development FUJI PHOTO FILM CO., LTD. (JP) 1978-10-24 US claimed