Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM2 | Q14416 | 1/20 | 0.36 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.33 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | PDE2A | O00408 | 1/20 | 0.32 |
| ▸ | RORC | P51449 | 2/20 | 0.32 |
| ▸ | PDK2 | Q15119 | 2/20 | 0.32 |
| ▸ | GCGR | P47871 | 6/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | ARF6 | P62330 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20393105 | 0.92 | GRM2 (0.35) | GRM2PRMT5WDR77NPSR1PDE2A | |
| SCHEMBL18638652 | 0.92 | GRM2 (0.36) | GRM2PRMT5WDR77NPSR1PDE2A | |
| SCHEMBL20393147 | 0.89 | APP (0.42) | GRM2RORC | |
| SCHEMBL18638639 | 0.87 | AHR (0.36) | PDK2 | |
| SCHEMBL18638358 | 0.85 | ALOX5AP (0.39) | RORCMEN1ALDH1A1GAAMAPT | |
| SCHEMBL18638540 | 0.85 | KIF11 (0.39) | MEN1ALDH1A1GAAMAPTMAPK1 | |
| SCHEMBL18638644 | 0.83 | SCN9A (0.39) | — | |
| SCHEMBL20393281 | 0.82 | PARP10 (0.38) | ALDH1A1MAPTL3MBTL1 | |
| SCHEMBL18638637 | 0.81 | FASN (0.34) | GRM2RORC | |
| SCHEMBL18638664 | 0.81 | APP (0.42) | GRM2RORC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017043636-A1 | NOVEL BENZIMIDAZOLE COMPOUND AND PHARMACEUTICAL USE OF SAME | 大日本住友製薬株式会社 | 2017-03-16 | — | — | WO | disclosed |