Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | NR4A2 | P43354 | 2/20 | 0.35 |
| ▸ | BRD4 | O60885 | 2/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | PKM | P14618 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | ADCY10 | Q96PN6 | 1/20 | 0.34 |
| ▸ | MAP3K5 | Q99683 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | CFTR | P13569 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1862734 | 0.86 | KDM4E (0.43) | GAAMAPTNPC1KDM4EALDH1A1 | |
| SCHEMBL596089 | 0.84 | GAA (0.40) | GAAMAPTNR4A2BRD4ADCY10 | |
| SCHEMBL1866000 | 0.83 | GAA (0.36) | GAALMNAPOLBPKM | |
| SCHEMBL23142702 | 0.80 | MAPT (0.40) | GAAMAPTLMNAPOLBNR4A2 | |
| SCHEMBL3296730 | 0.78 | MAPT (0.39) | GAAMAPTNR4A2BRD4NPC1 | |
| SCHEMBL3294649 | 0.78 | MAPT (0.39) | GAAMAPTLMNANR4A2BRD4 | |
| SCHEMBL6887159 | 0.75 | GAA (0.68) | GAAMAPTLMNAPOLBNR4A2 | |
| SCHEMBL3402435 | 0.73 | GAA (0.34) | GAA | |
| SCHEMBL30556712 | 0.73 | GAA (0.38) | GAAMAPTLMNAPOLBNR4A2 | |
| SCHEMBL6887971 | 0.72 | GAA (0.49) | GAAMAPTLMNAPOLBNR4A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7939673-B2 | Process for preparing 3-dihalomethyl-pyrazole-4-carboxylic acid derivatives | BAYER CROPSCIENCE AG (DE) | 2011-05-10 | — | — | US | disclosed |
| US-20090326242-A1 | PROCESS FOR PREPARING 3-DIHALOMETHYL-PYRAZOLE-4-CARBOXYLIC ACID DERIVATIVES | BAYER CROPSCIENCE AG (DE) | 2009-12-31 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090326242-A1 | PROCESS FOR PREPARING 3-DIHALOMETHYL-PYRAZOLE-4-CARBOXYLIC ACID DERIVATIVES | HRH4, SUV39H2, SUV39H1 | GAA 962/4885MAPT 3796/4885LMNA 4007/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.