Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | ADCY10 | Q96PN6 | 1/20 | 0.39 |
| ▸ | NR4A2 | P43354 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | F2 | P00734 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | GLA | P06280 | 2/20 | 0.36 |
| ▸ | BRD4 | O60885 | 1/20 | 0.36 |
| ▸ | CNR2 | P34972 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5720281 | 0.84 | BAZ2B (0.46) | GAALMNAKMT2AMEN1NPC1 | |
| SCHEMBL6887159 | 0.83 | GAA (0.68) | GAALMNAPOLBNR4A2MAPT | |
| SCHEMBL5720264 | 0.81 | POLB (0.41) | GAALMNAPOLBKMT2ARAB9A | |
| SCHEMBL27351594 | 0.77 | ADCY10 (0.43) | GAALMNAPOLBADCY10NR4A2 | |
| SCHEMBL4443917 | 0.75 | CNR2 (0.47) | GAAADCY10NR4A2KMT2AMAPT | |
| SCHEMBL841632 | 0.75 | GAA (0.51) | GAAPOLBNR4A2KMT2AMAPT | |
| SCHEMBL25409621 | 0.74 | KDM4E (0.43) | GAAADCY10NR4A2KMT2AMAPT | |
| SCHEMBL5653038 | 0.74 | GAA (0.42) | GAAADCY10NR4A2KMT2AMAPT | |
| SCHEMBL31499306 | 0.74 | GAA (0.42) | GAALMNAADCY10NR4A2KMT2A | |
| SCHEMBL23362881 | 0.74 | NR4A2 (0.40) | GAALMNAADCY10NR4A2KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106467492-B | preparation method of polyfluoromethyl pyrazole compound, intermediate and preparation method | 联化科技(盐城)有限公司 | 2019-12-17 | — | — | CN | disclosed |
| CN-100338029-C | Method for producing 2-halogenacyl-3-amino-acrylic acid derivatives | BAYER AG (DE) | 2007-09-19 | — | — | CN | disclosed |
| CN-1604889-A | Method for producing 2-halogenacyl-3-amino-acrylic acid derivatives | BAYER AG (DE) | 2005-04-06 | — | — | CN | disclosed |
| US-6706911-B1 | REACTING N-SUBSTITUTED 3-AMINOACRYLIC ESTERS WITH HALOALKYLCARBOXYLIC ANHYDRIDES IN PRESENCE OF BASE; PYRAZOLE-4-CARBOXYLIC ACID CHEMICAL INTERMEDIATES; HALOACYLATION | BAYER AKTIENGESELLSCHAFT (DE) | 2004-03-16 | — | — | US | disclosed |