Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CAMK2A | Q9UQM7 | 1/20 | 0.42 |
| ▸ | KIF11 | P52732 | 1/20 | 0.40 |
| ▸ | HSD17B3 | P37058 | 3/20 | 0.40 |
| ▸ | SRD5A1 | P18405 | 2/20 | 0.36 |
| ▸ | AKR1C3 | P42330 | 2/20 | 0.36 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.36 |
| ▸ | BRD4 | O60885 | 1/20 | 0.36 |
| ▸ | EDNRB | P24530 | 1/20 | 0.36 |
| ▸ | EDNRA | P25101 | 1/20 | 0.36 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.35 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.35 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.35 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.35 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.35 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.35 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.34 |
| ▸ | PNMT | P11086 | 1/20 | 0.34 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.34 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.34 |
| ▸ | DRD1 | P21728 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16099073 | 1.00 | CAMK2A (0.42) | CAMK2AKIF11HSD17B3SRD5A1AKR1C3 | |
| SCHEMBL28764376 | 0.85 | CAMK2A (0.46) | CAMK2ASRD5A1AKR1C3DRD1 | |
| SCHEMBL2898555 | 0.84 | KIF11 (0.38) | CAMK2AKIF11HSD17B3SRD5A1BRD4 | |
| SCHEMBL2917359 | 0.84 | KIF11 (0.38) | CAMK2AKIF11HSD17B3SRD5A1BRD4 | |
| SCHEMBL18940029 | 0.83 | CAMK2A (0.46) | CAMK2AKIF11HSD17B3SRD5A1AKR1C3 | |
| SCHEMBL2121418 | 0.82 | CAMK2A (0.40) | CAMK2AKIF11HSD17B3SRD5A1AKR1C3 | |
| SCHEMBL18940076 | 0.81 | KIF11 (0.40) | CAMK2AKIF11HSD17B3SRD5A1AKR1C3 | |
| SCHEMBL28386200 | 0.80 | NR1H2 (0.42) | ABHD6 | |
| SCHEMBL29410655 | 0.80 | NR1H2 (0.42) | ABHD6 | |
| SCHEMBL16099540 | 0.80 | NR1H2 (0.42) | ABHD6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017046605-A1 | ANTIBACTERIAL COMPOUNDS | REDX PHARMA PLC (GB) | 2017-03-23 | — | — | WO | disclosed |
| WO-2017046606-A1 | ANTIBACTERIAL COMPOUNDS | REDX PHARMA PLC (GB) | 2017-03-23 | — | — | WO | disclosed |