Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 4/20 | 0.65 |
| ▸ | DHODH | Q02127 | 4/20 | 0.65 |
| ▸ | MEN1 | O00255 | 3/20 | 0.65 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.65 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.65 |
| ▸ | NPC1 | O15118 | 3/20 | 0.58 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.53 |
| ▸ | GAA | P10253 | 2/20 | 0.53 |
| ▸ | KDR | P35968 | 1/20 | 0.53 |
| ▸ | HTT | P42858 | 1/20 | 0.53 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.52 |
| ▸ | EIF4H | Q15056 | 1/20 | 0.52 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.51 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.51 |
| ▸ | F10 | P00742 | 1/20 | 0.51 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.49 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3820618 | 0.88 | HTT (0.66) | RAB9ADHODHMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL18640758 | 0.85 | NPC1 (0.61) | RAB9ADHODHMEN1KMT2ANPC1 | |
| SCHEMBL18640720 | 0.85 | DHODH (0.65) | RAB9ADHODHMEN1KMT2ANPC1 | |
| SCHEMBL6612630 | 0.85 | HTT (0.56) | RAB9ADHODHMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL1307493 | 0.85 | DHODH (0.56) | RAB9ADHODHMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL1307643 | 0.85 | MEN1 (0.63) | RAB9ADHODHMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL18640743 | 0.83 | HTT (0.61) | RAB9ADHODHMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL18640742 | 0.83 | DHODH (0.57) | RAB9ADHODHMEN1KMT2ANPC1 | |
| SCHEMBL4193561 | 0.82 | DHODH (0.51) | RAB9ADHODHMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL18640731 | 0.82 | RAB9A (0.67) | RAB9AMEN1KMT2ASMN1; SMN2NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3362436-B1 | PROCESS FOR THE CATALYTIC DIRECTED CLEAVAGE OF AMIDE-CONTAINING COMPOUNDS | UNIV ANTWERPEN (BE) | 2021-06-30 | — | — | EP | disclosed |
| EP-3362436-A1 | PROCESS FOR THE CATALYTIC DIRECTED CLEAVAGE OF AMIDE-CONTAINING COMPOUNDS | Universiteit Antwerpen (BE) | 2018-08-22 | — | — | EP | disclosed |
| WO-2017046133-A1 | PROCESS FOR THE CATALYTIC DIRECTED CLEAVAGE OF AMIDE-CONTAINING COMPOUNDS | UNIVERSITEIT ANTWERPEN (BE) | 2017-03-23 | — | — | WO | disclosed |