Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR4 | O00206 | 5/20 | 0.43 |
| ▸ | GRM5 | P41594 | 1/20 | 0.31 |
| ▸ | MRGPRX1 | Q96LB2 | 1/20 | 0.31 |
| ▸ | NAMPT | P43490 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1862043 | 0.88 | TLR4 (0.48) | TLR4MRGPRX1 | |
| SCHEMBL1863031 | 0.87 | TLR4 (0.46) | TLR4MRGPRX1 | |
| SCHEMBL1864588 | 0.87 | TLR4 (0.46) | TLR4MRGPRX1 | |
| SCHEMBL1862994 | 0.86 | TLR4 (0.47) | TLR4MRGPRX1 | |
| SCHEMBL4147590 | 0.85 | TLR4 (0.46) | TLR4GRM5MRGPRX1NAMPT | |
| SCHEMBL1866347 | 0.83 | TLR4 (0.47) | TLR4MRGPRX1 | |
| SCHEMBL1862851 | 0.83 | TLR4 (0.47) | TLR4MRGPRX1 | |
| SCHEMBL15093794 | 0.83 | TLR4 (0.47) | TLR4MRGPRX1 | |
| SCHEMBL1869909 | 0.80 | TLR4 (0.44) | TLR4MRGPRX1 | |
| SCHEMBL1864172 | 0.80 | TLR4 (0.57) | TLR4GRM5MRGPRX1NAMPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7935835-B2 | Substituted cycloalkene derivative | DAIICHI SANKYO COMPANY, LIMITED (JP) | 2011-05-03 | — | — | US | disclosed |