Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | TSHR | P16473 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | MPO | P05164 | 1/20 | 0.49 |
| ▸ | BLM | P54132 | 1/20 | 0.49 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.49 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | CASP1 | P29466 | 1/20 | 0.46 |
| ▸ | CASP7 | P55210 | 1/20 | 0.46 |
| ▸ | EGFR | P00533 | 3/20 | 0.46 |
| ▸ | SRC | P12931 | 1/20 | 0.46 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.46 |
| ▸ | ALPI | P09923 | 1/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28569616 | 0.88 | KDM4E (0.50) | MAPTKDM4EMEN1TSHRKMT2A | |
| SCHEMBL28569615 | 0.88 | KDM4E (0.50) | MAPTKDM4EMEN1TSHRKMT2A | |
| SCHEMBL30678518 | 0.88 | KDM4E (0.50) | MAPTKDM4EMEN1TSHRKMT2A | |
| SCHEMBL31161279 | 0.88 | KDM4E (0.50) | MAPTKDM4EMEN1TSHRKMT2A | |
| SCHEMBL29499673 | 0.83 | MAPT (0.61) | MAPTKDM4EMEN1TSHRKMT2A | |
| SCHEMBL4586167 | 0.83 | MAPT (0.61) | MAPTKDM4EMEN1TSHRKMT2A | |
| SCHEMBL29557291 | 0.83 | MAPT (0.61) | MAPTKDM4EMEN1TSHRKMT2A | |
| SCHEMBL2049320 | 0.83 | MAPT (0.61) | MAPTKDM4EMEN1TSHRKMT2A | |
| SCHEMBL29527665 | 0.83 | MAPT (0.61) | MAPTKDM4EMEN1TSHRKMT2A | |
| SCHEMBL195997 | 0.83 | MAPT (0.61) | MAPTKDM4EMEN1TSHRKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4684030-A2 | METHOD OF DEPROTECTING AT LEAST ONE D-AMINO ACID AND/OR D-AMINO ACID DERIVATIVE PROTECTED FUNCTIONAL GROUP | Martin-Luther-Universität Halle-Wittenberg (DE) | 2026-01-28 | — | — | EP | disclosed |
| WO-2024227957-A2 | METHOD OF DEPROTECTING AT LEAST ONE D-AMINO ACID AND/OR D-AMINO ACID DERIVATIVE PROTECTED FUNCTIONAL GROUP | Martin-Luther-Universität Halle-Wittenberg (DE) | 2024-11-07 | — | — | WO | disclosed |
| CN-115181164-A | Derivatives of amatoxins and their coupling to cell binding molecules | 杭州多禧生物科技有限公司 | 2022-10-14 | — | — | CN | disclosed |
| CN-109689107-B | Derivatives of amatoxins and their coupling to cell binding molecules | 杭州多禧生物科技有限公司 | 2022-08-16 | — | — | CN | disclosed |
| US-10836796-B2 | Derivatives of amanita toxins and their conjugation to a cell binding molecule | HANGZHOU DAC BIOTECH CO., LTD. (CN) | 2020-11-17 | — | — | US | disclosed |
| US-20200079820-A1 | DERIVATIVES OF AMANITA TOXINS AND THEIR CONJUGATION TO A CELL BINDING MOLECULE | HANGZHOU DAC BIOTECH CO., LTD. (CN) | 2020-03-12 | — | — | US | disclosed |
| WO-2017046658-A1 | DERIVATIVES OF AMANITA TOXINS AND THEIR CONJUGATION TO A CELL BINDING MOLECULE | HANGZHOU DAC BIOTECH CO, LTD (CN) | 2017-03-23 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200079820-A1 | DERIVATIVES OF AMANITA TOXINS AND THEIR CONJUGATION TO A CELL BINDING MOLECULE | ANTXR2, ANXA5, C3AR1 | MAPT 3010/4885KDM4E 3063/4885MEN1 260/4885 |
| US-10836796-B2 | Derivatives of amanita toxins and their conjugation to a cell binding molecule | ANTXR2, ANXA5, C3AR1 | MAPT 3086/4885KDM4E 2965/4885MEN1 278/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.