Sugi Predict

Sugi Predict / Compounds / SCHEMBL4586167

SCHEMBL4586167

SCHEMBL4586167

Cc1[nH]c2ccccc2c1C[C@@H](N)C(=O)O

nearest known ligand 0.61

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ MAPT P10636 6/20 0.61
▸ KDM4E B2RXH2 3/20 0.61
▸ ALDH1A1 P00352 3/20 0.61
▸ GAA P10253 1/20 0.61
▸ CASP1 P29466 1/20 0.61
▸ CASP7 P55210 1/20 0.61
▸ TSHR P16473 3/20 0.54
▸ MEN1 O00255 2/20 0.54
▸ KMT2A Q03164 2/20 0.54
▸ LMNA P02545 1/20 0.54
▸ MPO P05164 1/20 0.54
▸ BLM P54132 1/20 0.54
▸ PMP22 Q01453 1/20 0.54
▸ HIF1A Q16665 1/20 0.54
▸ HTT P42858 2/20 0.53
▸ POLB P06746 1/20 0.51
▸ CYP3A4 P08684 1/20 0.50
▸ EGFR P00533 2/20 0.49
▸ SRC P12931 1/20 0.49
▸ SCN9A Q15858 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29499673 1.00 MAPT (0.61) MAPTKDM4EALDH1A1GAACASP1
SCHEMBL29557291 1.00 MAPT (0.61) MAPTKDM4EALDH1A1GAACASP1
SCHEMBL195997 1.00 MAPT (0.61) MAPTKDM4EALDH1A1GAACASP1
SCHEMBL29527665 1.00 MAPT (0.61) MAPTKDM4EALDH1A1GAACASP1
SCHEMBL2049320 1.00 MAPT (0.61) MAPTKDM4EALDH1A1GAACASP1
SCHEMBL7527587 0.88 SCN9A (0.58) MAPTKDM4EALDH1A1GAACASP1
SCHEMBL7811480 0.85 MAPT (0.54) MAPTKDM4EALDH1A1GAACASP1
SCHEMBL27312034 0.85 MAPT (0.54) MAPTKDM4EALDH1A1GAACASP1
SCHEMBL5925150 0.85 MAPT (0.54) MAPTKDM4EALDH1A1GAACASP1
SCHEMBL18029219 0.84 FDPS (0.47) MAPTKDM4EALDH1A1GAACASP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 100 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240400499-A1 NOVEL AMINO ACID DERIVATIVES PEPTIDREAM INC (JP) 2024-12-05 — — US claimed
US-20060217316-A1 Method for the treatment of prostate cancer GENIX THERAPEUTICS, INC. 2006-09-28 — — US claimed
WO-2004087190-A1 METHOD FOR THE TREATMENT OF PROSTATE CANCER GENIX THERAPEUTICS INC. (US) 2004-10-14 — — WO claimed
CN-1390230-A Peptides for the Treatment of Erectile Dysfunction ZANTARIS AG (DE) 2003-01-08 — — CN claimed
EP-1246836-A2 PEPTIDES FOR TREATMENT OF ERECTILE DYSFUNCTION Ardana Bioscience Limited (GB) 2002-10-09 — — EP claimed
WO-2001034171-A2 PEPTIDES FOR TREATMENT OF ERECTILE DYSFUNCTION ZENTARIS AG (DE) 2001-05-17 — — WO claimed
US-6211156-B1 ADMINISTERING DI-, TRI-, AND TETRAPEPTIDES TERMINATED AT CARBOXYL END WITH PRIMARY AMINO GROUP TO TREAT IMPOTENCY; SIDE EFFECT REDUCTION ASTA MEDICA A.G. (DE) 2001-04-03 — — US claimed
US-20260042715-A1 FLUORINATION PROCESS ROYAL COLLEGE OF SURGEONS IN IRELAND (IE) 2026-02-12 — — US disclosed
US-12441760-B2 Amino diacids containing peptide modifiers CHEMICAL & BIOPHARMACEUTICAL LABORATORIES OF PATRAS S.A. (GR) 2025-10-14 — — US disclosed
CN-120202010-A Ligand-oligonucleotide conjugates and linkers for use therewith 上海京新生物医药有限公司 2025-06-24 — — CN disclosed
US-20250188115-A1 PROCESS FOR PREPARING A GLUCAGON-LIKE PEPTIDE CHEMICAL & BIOPHARMACEUTICAL LABORATORIES OF PATRAS S.A. (GR) 2025-06-12 — — US disclosed
EP-4565550-A1 FLUORINATION PROCESS Royal College of Surgeons in Ireland (IE) 2025-06-11 — — EP disclosed
US-20240400499-A1 NOVEL AMINO ACID DERIVATIVES PEPTIDREAM INC (JP) 2024-12-05 — — US disclosed
US-5646301-A INCORPORATION INTO PEPTIDES Deghenghi, Romano (CH) 1997-07-08 — — US disclosed
US-5635379-A PREPARED FROM N-ALPHA-ACETYL-2-ALKYL TRYPTOPHAN RACEMIC MIXTURE Deghenghi, Romano (CH) 1997-06-03 — — US disclosed
CN-1143647-A Dipeptides which promote release of growth hormone PFIZER (US) 1997-02-26 — — CN disclosed
WO-1996038471-A1 DIPEPTIDES WHICH PROMOTE RELEASE OF GROWTH HORMONE PFIZER INC. (US) 1996-12-05 — — WO disclosed
WO-1996035713-A1 DIPEPTIDES WHICH PROMOTE RELEASE OF GROWTH HORMONE PFIZER, INC. (US) 1996-11-14 — — WO disclosed
US-5329013-A Process for the preparation of tricyclo-[3.3.1.13,7 ]dec-2-yl-[R-(R*,R*)]-3-(1H-indol-3-ylmethyl)-3-methyl-4,9-dioxo-7,11-diphenyl-10-oxa-2,5,8-triazaundecanate GODECKE AKTIENGESELLSCHAFT (DE) 1994-07-12 — — US disclosed
CN-1049165-A The cycloalkyl that N-replaces and the tryptophane-phenylalanine of multi-ring alkyl alpha-substitution-and phenylethylamine derivative WARNER LAMBERT CO (US) 1991-02-13 — — CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12441760-B2 Amino diacids containing peptide modifiers PTMS, PEPD, NGLY1 MAPT 3530/4885KDM4E 2180/4885ALDH1A1 4400/4885
US-20260042715-A1 FLUORINATION PROCESS XDH, VGF, GTF2F1 MAPT 4812/4885KDM4E 3208/4885ALDH1A1 3039/4885
US-20250188115-A1 PROCESS FOR PREPARING A GLUCAGON-LIKE PEPTIDE GLP1R, IAPP, GCG MAPT 4749/4885KDM4E 3735/4885ALDH1A1 4794/4885
US-20240400499-A1 NOVEL AMINO ACID DERIVATIVES BCAT1, BCAT2, PELP1 MAPT 1809/4885KDM4E 3586/4885ALDH1A1 4472/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.