Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 2/20 | 0.50 |
| ▸ | NPC1 | O15118 | 1/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 1/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.50 |
| ▸ | PTGS2 | P35354 | 4/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | GPR84 | Q9NQS5 | 2/20 | 0.45 |
| ▸ | SKP2 | Q13309 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 3/20 | 0.39 |
| ▸ | CA1 | P00915 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | CA9 | Q16790 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7041323 | 0.95 | HPGD (0.50) | HPGDNPC1MAPK1HTTRAB9A | |
| SCHEMBL2002090 | 0.87 | HPGD (0.61) | HPGDNPC1MAPK1HTTRAB9A | |
| SCHEMBL68667 | 0.85 | PTGS2 (0.64) | HPGDNPC1MAPK1HTTRAB9A | |
| SCHEMBL27994037 | 0.84 | HPGD (0.58) | HPGDNPC1MAPK1HTTRAB9A | |
| SCHEMBL6534660 | 0.81 | HPGD (0.56) | HPGDNPC1MAPK1HTTRAB9A | |
| SCHEMBL1187465 | 0.79 | HPGD (0.54) | HPGDNPC1MAPK1HTTRAB9A | |
| SCHEMBL28161119 | 0.79 | HPGD (0.54) | HPGDNPC1MAPK1HTTRAB9A | |
| SCHEMBL22080498 | 0.79 | PTGS2 (0.74) | HPGDNPC1MAPK1HTTRAB9A | |
| SCHEMBL2871788 | 0.78 | PTGS2 (0.68) | HPGDNPC1MAPK1HTTRAB9A | |
| SCHEMBL29047721 | 0.78 | HPGD (0.48) | HPGDNPC1MAPK1HTTRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3350189-A1 | METAL COMPLEXES | UEA Enterprises Limited (GB) | 2018-07-25 | — | — | EP | disclosed |
| WO-2017046572-A1 | METAL COMPLEXES | UNIVERSITY OF EAST ANGLIA (GB) | 2017-03-23 | — | — | WO | disclosed |