⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9537477 | 0.72 | — | — | |
| SCHEMBL13264701 | 0.65 | — | — | |
| SCHEMBL13139145 | 0.62 | — | — | |
| SCHEMBL4547000 | 0.53 | NOS3 (0.30) | — | |
| SCHEMBL14123807 | 0.53 | — | — | |
| SCHEMBL2179725 | 0.51 | — | — | |
| SCHEMBL2798222 | 0.51 | — | — | |
| SCHEMBL9776890 | 0.51 | — | — | |
| SCHEMBL15359623 | 0.51 | — | — | |
| SCHEMBL22207480 | 0.49 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2440550-B1 | INDOLE AMIDE DERIVATIVES AND RELATED COMPOUNDS FOR USE IN THE TREATMENT OF NEURODEGENERATIVE DISEASES | UNIV LEUVEN KATH (BE) | 2017-03-15 | — | — | EP | disclosed |