Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.47 |
| ▸ | RORC | P51449 | 1/20 | 0.46 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | SLC6A9 | P48067 | 6/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | GFER | P55789 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | MGAM | O43451 | 1/20 | 0.39 |
| ▸ | SI | P14410 | 1/20 | 0.39 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.39 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14683695 | 1.00 | HSD17B10 (0.47) | HSD17B10RORCNR4A2ALDH1A1GAA | |
| SCHEMBL30014395 | 0.89 | NR4A2 (0.45) | HSD17B10RORCNR4A2ALDH1A1GAA | |
| SCHEMBL8512426 | 0.84 | HSD17B10 (0.52) | HSD17B10NR4A2ALDH1A1GAASMN1; SMN2 | |
| SCHEMBL15270595 | 0.82 | HSD17B10 (0.51) | HSD17B10NR4A2ALDH1A1GAASMN1; SMN2 | |
| SCHEMBL29849022 | 0.82 | HSD17B10 (0.51) | HSD17B10NR4A2ALDH1A1GAASMN1; SMN2 | |
| SCHEMBL2825210 | 0.80 | SLC6A9 (0.62) | SLC6A9 | |
| SCHEMBL2826299 | 0.80 | SLC6A9 (0.62) | SLC6A9 | |
| SCHEMBL2823933 | 0.80 | SLC6A9 (0.62) | SLC6A9 | |
| SCHEMBL31426250 | 0.80 | HSD17B10 (0.49) | HSD17B10NR4A2ALDH1A1GAASMN1; SMN2 | |
| SCHEMBL14027054 | 0.80 | HSD17B10 (0.49) | HSD17B10NR4A2ALDH1A1GAASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2739615-B1 | PHENYL-3-AZA-BICYCLO[3.1.0]HEX-3-YL-METHANONES AND THE USE THEREOF AS MEDICAMENT | BOEHRINGER INGELHEIM INT (DE) | 2017-03-15 | — | — | EP | disclosed |