Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAP3K14 | Q99558 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.36 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | APEX1 | P27695 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
| ▸ | IDO1 | P14902 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11719476 | 0.98 | MAP3K14 (0.46) | MAP3K14MAPTCRBNCYP19A1MEN1 | |
| SCHEMBL11384813 | 0.84 | MAP3K14 (0.52) | MAP3K14MAPTCRBNCYP19A1MEN1 | |
| SCHEMBL11384807 | 0.84 | MAP3K14 (0.52) | MAP3K14MAPTCRBNCYP19A1MEN1 | |
| SCHEMBL5909391 | 0.80 | MAP3K14 (0.55) | MAP3K14MAPTCRBNCYP19A1MEN1 | |
| SCHEMBL5556075 | 0.78 | MAP3K14 (0.41) | MAP3K14CRBN | |
| Bicarbonate SCHEMBL28708130 | 0.78 | MAP3K14 (0.34) | MAP3K14MEN1APEX1KMT2ATDP1 | |
| SCHEMBL18261248 | 0.72 | MAP3K14 (0.35) | MAP3K14 | |
| SCHEMBL9484357 | 0.72 | MAP3K14 (0.35) | MAP3K14CRBN | |
| SCHEMBL9998408 | 0.72 | MAP3K14 (0.35) | MAP3K14 | |
| SCHEMBL28541981 | 0.71 | MAP3K14 (0.46) | MAP3K14MAPTCRBNKMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2793928-B1 | PROCESS FOR PURIFYING A SAMPLE OF H38C2 ANTIBODY | PFIZER (US) | 2017-03-15 | — | — | EP | disclosed |