Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAP3K14 | Q99558 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3942148 | 0.76 | — | — | |
| SCHEMBL18643159 | 0.72 | MAP3K14 (0.48) | MAP3K14 | |
| SCHEMBL11719476 | 0.70 | MAP3K14 (0.46) | MAP3K14 | |
| SCHEMBL5909391 | 0.66 | MAP3K14 (0.55) | MAP3K14 | |
| SCHEMBL5556075 | 0.65 | MAP3K14 (0.41) | MAP3K14 | |
| SCHEMBL733638 | 0.63 | MEN1 (0.32) | — | |
| SCHEMBL6341441 | 0.62 | — | — | |
| SCHEMBL5504847 | 0.61 | — | — | |
| SCHEMBL6651767 | 0.60 | MAP3K14 (0.43) | MAP3K14 | |
| SCHEMBL11384807 | 0.59 | MAP3K14 (0.52) | MAP3K14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2582692-A1 | CYCLOHEXYL-AZETIDINYL ANTAGONISTS OF CCR2 | Janssen Pharmaceutica, N.V. (BE) | 2013-04-24 | — | — | EP | disclosed |
| WO-2011159854-A1 | CYCLOHEXYL-AZETIDINYL ANTAGONISTS OF CCR2 | JANSSEN PHARMACEUTICA NV (BE) | 2011-12-22 | — | — | WO | disclosed |