⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21784160 | 0.86 | — | — | |
| SCHEMBL21784168 | 0.80 | — | — | |
| SCHEMBL21784170 | 0.79 | — | — | |
| SCHEMBL23455632 | 0.78 | SMN1; SMN2 (0.31) | — | |
| SCHEMBL22545678 | 0.76 | SMN1; SMN2 (0.32) | — | |
| SCHEMBL23454203 | 0.76 | SMN1; SMN2 (0.32) | — | |
| SCHEMBL22545662 | 0.76 | SMN1; SMN2 (0.32) | — | |
| SCHEMBL19363808 | 0.71 | — | — | |
| SCHEMBL18643169 | 0.71 | — | — | |
| SCHEMBL21233395 | 0.70 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2440550-B1 | INDOLE AMIDE DERIVATIVES AND RELATED COMPOUNDS FOR USE IN THE TREATMENT OF NEURODEGENERATIVE DISEASES | UNIV LEUVEN KATH (BE) | 2017-03-15 | — | — | EP | disclosed |