⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23455632 | 0.89 | SMN1; SMN2 (0.31) | — | |
| SCHEMBL21784160 | 0.87 | — | — | |
| SCHEMBL22545662 | 0.87 | SMN1; SMN2 (0.32) | — | |
| SCHEMBL25913921 | 0.87 | SMN1; SMN2 (0.32) | — | |
| SCHEMBL22545678 | 0.87 | SMN1; SMN2 (0.32) | — | |
| SCHEMBL23454203 | 0.87 | SMN1; SMN2 (0.32) | — | |
| SCHEMBL18643232 | 0.79 | — | — | |
| SCHEMBL21720486 | 0.79 | SMN1; SMN2 (0.31) | — | |
| SCHEMBL21720477 | 0.79 | SMN1; SMN2 (0.31) | — | |
| SCHEMBL21110282 | 0.78 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20200071327-A1 | Prodrugs for the Treatment of Disease | OPPILAN PHARMA LTD (GB) | 2020-03-05 | — | — | US | disclosed |