Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCHR1 | Q99705 | 3/20 | 0.34 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | MEN1 | O00255 | 3/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | TLR4 | O00206 | 4/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | IDH1 | O75874 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | UBE2M | P61081 | 1/20 | 0.30 |
| ▸ | DCUN1D1 | Q96GG9 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1868616 | 0.86 | TLR4 (0.35) | TLR4 | |
| SCHEMBL1862851 | 0.86 | TLR4 (0.47) | PKMKMT2ATLR4NPC1RAB9A | |
| SCHEMBL1865697 | 0.86 | TLR4 (0.34) | TLR4 | |
| SCHEMBL1866347 | 0.86 | TLR4 (0.47) | PKMKMT2ATLR4NPC1RAB9A | |
| SCHEMBL15093794 | 0.86 | TLR4 (0.47) | PKMKMT2ATLR4NPC1RAB9A | |
| SCHEMBL1869582 | 0.86 | TLR4 (0.37) | TLR4NPC1RAB9AUBE2MDCUN1D1 | |
| SCHEMBL1865198 | 0.84 | TLR4 (0.37) | TLR4SMN1; SMN2 | |
| SCHEMBL1863516 | 0.84 | TLR4 (0.37) | TLR4SMN1; SMN2 | |
| SCHEMBL1862291 | 0.84 | TLR4 (0.33) | TSHRTLR4 | |
| SCHEMBL1869232 | 0.83 | TLR4 (0.38) | TLR4MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7935835-B2 | Substituted cycloalkene derivative | DAIICHI SANKYO COMPANY, LIMITED (JP) | 2011-05-03 | — | — | US | disclosed |