Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR4 | O00206 | 5/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1865697 | 0.96 | TLR4 (0.34) | TLR4 | |
| SCHEMBL1867519 | 0.95 | TLR4 (0.33) | TLR4 | |
| SCHEMBL1862851 | 0.90 | TLR4 (0.47) | TLR4 | |
| SCHEMBL1866347 | 0.90 | TLR4 (0.47) | TLR4 | |
| SCHEMBL15093794 | 0.90 | TLR4 (0.47) | TLR4 | |
| SCHEMBL1864418 | 0.86 | MCHR1 (0.34) | TLR4 | |
| SCHEMBL1869861 | 0.85 | MAPT (0.31) | — | |
| SCHEMBL1869582 | 0.85 | TLR4 (0.37) | TLR4 | |
| SCHEMBL1865198 | 0.85 | TLR4 (0.37) | TLR4 | |
| SCHEMBL1863516 | 0.85 | TLR4 (0.37) | TLR4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7935835-B2 | Substituted cycloalkene derivative | DAIICHI SANKYO COMPANY, LIMITED (JP) | 2011-05-03 | — | — | US | disclosed |