Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14279380 | 1.00 | CTSK (0.56) | CTSKCTSS | |
| SCHEMBL29506103 | 0.95 | CTSK (0.51) | CTSKCTSS | |
| SCHEMBL28523886 | 0.93 | CTSK (0.50) | CTSKCTSS | |
| SCHEMBL30901642 | 0.93 | CTSK (0.50) | CTSKCTSS | |
| SCHEMBL28012265 | 0.93 | CTSK (0.56) | CTSKCTSS | |
| SCHEMBL13669545 | 0.93 | CTSK (0.54) | CTSKCTSS | |
| SCHEMBL18993567 | 0.92 | CTSK (0.55) | CTSKCTSS | |
| SCHEMBL31121751 | 0.91 | CTSK (0.54) | CTSKCTSS | |
| SCHEMBL31121749 | 0.91 | CTSK (0.54) | CTSKCTSS | |
| SCHEMBL8288056 | 0.90 | CTSK (0.47) | CTSKCTSS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170342035-A1 | 2-AMINOPYRIMIDINE DERIVATIVES FOR THE TREATMENT OF VIRAL INFECTIONS | JANSSEN SCIENCES IRELAND UC (IE) | 2017-11-30 | — | — | US | disclosed |
| US-9598378-B2 | 2-aminopyrimidine derivatives for the treatment of viral infections | JANSSEN SCIENCES IRELAND UC (IE) | 2017-03-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170342035-A1 | 2-AMINOPYRIMIDINE DERIVATIVES FOR THE TREATMENT OF VIRAL INFECTIONS | DPYD, EIF2AK2, TYMP | CTSK 3549/4885CTSS 3182/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.