Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 2/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | APEX1 | P27695 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 2/20 | 0.32 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.32 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.32 |
| ▸ | LTB4R | Q15722 | 5/20 | 0.32 |
| ▸ | LTB4R2 | Q9NPC1 | 5/20 | 0.32 |
| ▸ | PPARA | Q07869 | 6/20 | 0.32 |
| ▸ | PPARG | P37231 | 4/20 | 0.31 |
| ▸ | CNR1 | P21554 | 1/20 | 0.30 |
| ▸ | CNR2 | P34972 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18646772 | 0.95 | POLB (0.34) | IDO1POLBAPEX1HTTTDP1 | |
| SCHEMBL18646494 | 0.93 | TSHR (0.32) | IDO1POLBAPEX1HTTTDP1 | |
| SCHEMBL18646514 | 0.93 | IDO1 (0.35) | IDO1CYP2C9POLBAPEX1HTT | |
| SCHEMBL18646491 | 0.92 | PPARG (0.33) | POLBAPEX1HTTTDP1TSHR | |
| SCHEMBL18646492 | 0.92 | TSHR (0.33) | IDO1POLBAPEX1HTTTDP1 | |
| SCHEMBL18646500 | 0.91 | THRA (0.36) | IDO1POLBAPEX1HTTTDP1 | |
| SCHEMBL18645800 | 0.90 | POLB (0.34) | IDO1CYP2C9POLBAPEX1HTT | |
| SCHEMBL20286031 | 0.90 | THRA (0.37) | POLBAPEX1HTTTDP1TSHR | |
| SCHEMBL21098137 | 0.90 | POLB (0.38) | POLBAPEX1HTTTDP1TSHR | |
| SCHEMBL18647070 | 0.90 | TSHR (0.32) | IDO1POLBAPEX1HTTTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11214736-B2 | Liquid-crystalline medium | MERCK PATENT GMBH (DE) | 2022-01-04 | — | — | US | disclosed |
| US-20180171231-A1 | LIQUID-CRYSTALLINE MEDIUM | MERCK PATENT GMBH (DE) | 2018-06-21 | — | — | US | disclosed |
| US-20180171231-A1 | LIQUID-CRYSTALLINE MEDIUM | MERCK PATENT GMBH (DE) | 2018-06-21 | — | — | US | disclosed |
| WO-2017041893-A1 | LIQUID-CRYSTALLINE MEDIUM | MERCK PATENT GMBH (DE) | 2017-03-16 | — | — | WO | disclosed |