Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | RNPEP | Q9H4A4 | 1/20 | 0.32 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.32 |
| ▸ | PDE4A | P27815 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6409663 | 0.81 | TP53 (0.43) | TP53RNPEPSLC7A5 | |
| SCHEMBL15693950 | 0.80 | PDE4A (0.46) | TP53PDE4A | |
| SCHEMBL14817422 | 0.80 | PDE4A (0.46) | TP53PDE4A | |
| SCHEMBL4224484 | 0.80 | TP53 (0.38) | TP53PDE4A | |
| SCHEMBL16994741 | 0.80 | PDE4A (0.46) | TP53PDE4A | |
| SCHEMBL17054001 | 0.80 | PDE4A (0.46) | TP53PDE4A | |
| SCHEMBL6742696 | 0.80 | TP53 (0.38) | TP53PDE4A | |
| SCHEMBL3293344 | 0.80 | TP53 (0.38) | TP53PDE4A | |
| SCHEMBL18646758 | 0.77 | GRIK1 (0.31) | — | |
| SCHEMBL5681312 | 0.77 | CHRM1 (0.43) | TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10961513-B2 | Methods and compositions for recombinase-based genetic diversification | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2021-03-30 | — | — | US | disclosed |
| US-20190024099-A1 | METHODS AND COMPOSITIONS FOR RECOMBINASE-BASED GENETIC DIVERSIFICATION | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2019-01-24 | — | — | US | disclosed |
| WO-2017044476-A1 | METHODS AND COMPOSITIONS FOR RECOMBINASE-BASED GENETIC DIVERSIFICATION | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2017-03-16 | — | — | WO | disclosed |