Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | RNPEP | Q9H4A4 | 1/20 | 0.37 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.37 |
| ▸ | SLC1A3 | P43003 | 2/20 | 0.33 |
| ▸ | SLC1A2 | P43004 | 2/20 | 0.33 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | FOLH1 | Q04609 | 2/20 | 0.32 |
| ▸ | NAALAD2 | Q9Y3Q0 | 2/20 | 0.32 |
| ▸ | ENPEP | Q07075 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12951566 | 0.89 | TP53 (0.47) | TP53RNPEPSLC7A5SLC1A3SLC1A2 | |
| SCHEMBL7803516 | 0.84 | RNPEP (0.48) | TP53RNPEPSLC7A5SLC1A3SLC1A2 | |
| SCHEMBL7803514 | 0.84 | RNPEP (0.48) | TP53RNPEPSLC7A5SLC1A3SLC1A2 | |
| SCHEMBL9581116 | 0.82 | NAALAD2 (0.45) | TP53RNPEPSLC7A5FOLH1NAALAD2 | |
| SCHEMBL18646756 | 0.81 | TP53 (0.36) | TP53RNPEPSLC7A5 | |
| SCHEMBL16600087 | 0.79 | TSHR (0.45) | TP53RNPEPSLC7A5SLC1A3SLC1A2 | |
| SCHEMBL1869405 | 0.76 | — | — | |
| SCHEMBL5499838 | 0.76 | — | — | |
| SCHEMBL18562028 | 0.76 | — | — | |
| SCHEMBL667584 | 0.76 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1602727-A2 | Novel erythromycins and process for their preparation | Biotica Technology Limited (GB) | 2005-12-07 | — | — | EP | disclosed |
| EP-0909327-B1 | ERYTHROMYCINS AND PROCESS FOR THEIR PREPARATION | BIOTICA TECH LTD (GB) | 2005-06-01 | — | — | EP | disclosed |