SCHEMBL18647352

SCHEMBL18647352

Brc1ccc2nc(-c3ccccc3)c3ccccc3c2c1

nearest known ligand 0.62

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PRNP P04156 2/20 0.62
L3MBTL1 Q9Y468 1/20 0.55
DCLK1 O15075 1/20 0.53
PRKD3 O94806 1/20 0.53
MAP4K4 O95819 1/20 0.53
CHEK2 O96017 1/20 0.53
CSF1R P07333 1/20 0.53
FER P16591 1/20 0.53
CDK2 P24941 1/20 0.53
MARK3 P27448 1/20 0.53
FLT4 P35916 1/20 0.53
FLT3 P36888 1/20 0.53
MAPK9 P45984 1/20 0.53
CSNK1D P48730 1/20 0.53
CLK2 P49760 1/20 0.53
CSNK2A1 P68400 1/20 0.53
CSNK1G2 P78368 1/20 0.53
MAP4K2 Q12851 1/20 0.53
STK3 Q13188 1/20 0.53
CAMK2B Q13554 1/20 0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18647353 0.89 PRNP (0.55) PRNPL3MBTL1DCLK1PRKD3MAP4K4
SCHEMBL12578343 0.83 CYP1B1 (0.51) PRNPL3MBTL1ATMKMT2ARXFP1
SCHEMBL20245111 0.82 NUDT1 (0.50) PRNPL3MBTL1ATMKMT2AMAPT
SCHEMBL28231176 0.82 CFTR (0.49) PRNPL3MBTL1DCLK1PRKD3MAP4K4
SCHEMBL18455642 0.82 PRNP (0.63) PRNPL3MBTL1DCLK1PRKD3MAP4K4
SCHEMBL17752427 0.81 PRNP (0.45) PRNPL3MBTL1ATMKMT2ARXFP1
SCHEMBL3317867 0.81 KMT2A (0.61) PRNPL3MBTL1DCLK1PRKD3MAP4K4
SCHEMBL24108900 0.81 PRNP (0.61) PRNPL3MBTL1DCLK1PRKD3MAP4K4
SCHEMBL4558537 0.80 KMT2A (0.55) L3MBTL1ATMKMT2AMEN1ADORA2A
SCHEMBL729919 0.80 NUDT1 (0.61) L3MBTL1ATMKMT2AMAPTMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2018034443-A1 COMPOUND FOR ORGANIC ELECTRIC ELEMENT, ORGANIC ELECTRIC ELEMENT USING SAME, AND ELECTRONIC DEVICE THEREOF 덕산네오룩스 주식회사 2018-02-22 WO disclosed
WO-2017043797-A1 COMPOUND FOR ORGANIC ELECTRONIC ELEMENT, ORGANIC ELECTRONIC ELEMENT USING SAME, AND ELECTRONIC DEVICE THEREOF 덕산네오룩스 주식회사 2017-03-16 WO disclosed