SCHEMBL18648367

SCHEMBL18648367

CC(F)(F)C(F)(F)C(=O)OC12CC3CC(CC(C3)C1)C2

nearest known ligand 0.46

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
CYP19A1 P11511 4/20 0.46
CYP17A1 P05093 3/20 0.46
NAAA Q02083 1/20 0.37
NPSR1 Q6W5P4 3/20 0.36
MEN1 O00255 2/20 0.33
KMT2A Q03164 2/20 0.33
TSHR P16473 1/20 0.33
MAPK1 P28482 1/20 0.33
EPHX2 P34913 1/20 0.33
ALDH1A1 P00352 1/20 0.32
HTT P42858 1/20 0.32
LMNA P02545 1/20 0.32
GLA P06280 1/20 0.32
CA2 P00918 1/20 0.31
CACNA1H O95180 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL26061827 0.90 CYP19A1 (0.44) CYP19A1CYP17A1NAAANPSR1MEN1
SCHEMBL26061863 0.86 TSHR (0.51) CYP19A1CYP17A1NAAANPSR1TSHR
SCHEMBL686205 0.85 CYP19A1 (0.48) CYP19A1CYP17A1NAAANPSR1MEN1
SCHEMBL18467939 0.82 CYP19A1 (0.40) CYP19A1CYP17A1NAAANPSR1TSHR
SCHEMBL9764361 0.81 CYP19A1 (0.43) CYP19A1CYP17A1NAAANPSR1MEN1
SCHEMBL13232360 0.81 CYP19A1 (0.50) CYP19A1CYP17A1NAAANPSR1MEN1
SCHEMBL17545756 0.80 CYP19A1 (0.40) CYP19A1CYP17A1NAAANPSR1MEN1
SCHEMBL2680687 0.79 CYP19A1 (0.44) CYP19A1CYP17A1NAAANPSR1MEN1
SCHEMBL15452213 0.79 CYP19A1 (0.38) CYP19A1CYP17A1NAAANPSR1TSHR
SCHEMBL12346010 0.79 CYP19A1 (0.42) CYP19A1CYP17A1NAAANPSR1TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9599897-B2 Salt, resin, resist composition and method for producing resist pattern SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2017-03-21 US disclosed