Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR2 | Q92731 | 1/20 | 0.45 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | GPR119 | Q8TDV5 | 6/20 | 0.38 |
| ▸ | USP2 | O75604 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | STS | P08842 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1294022 | 0.88 | ESR2 (0.46) | ESR2NR1H2MEN1KMT2ANPC1 | |
| SCHEMBL18648629 | 0.88 | ESR2 (0.43) | ESR2NR1H2MEN1KMT2ANPC1 | |
| SCHEMBL1294555 | 0.86 | ESR2 (0.44) | ESR2NR1H2MEN1KMT2ANPC1 | |
| SCHEMBL12105512 | 0.85 | ESR2 (0.43) | ESR2NR1H2MEN1KMT2ANPC1 | |
| SCHEMBL12105508 | 0.83 | ESR2 (0.42) | ESR2NR1H2MEN1KMT2ANPC1 | |
| SCHEMBL12105516 | 0.83 | ESR2 (0.42) | ESR2NR1H2MEN1KMT2ANPC1 | |
| SCHEMBL12105518 | 0.83 | ESR2 (0.42) | ESR2NR1H2MEN1KMT2ANPC1 | |
| SCHEMBL1294622 | 0.82 | ESR2 (0.41) | ESR2NR1H2MEN1KMT2ANPC1 | |
| SCHEMBL18648627 | 0.82 | ESR2 (0.41) | ESR2NR1H2MEN1KMT2ANPC1 | |
| SCHEMBL12110032 | 0.81 | GPR119 (0.41) | ESR2NR1H2MEN1KMT2ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9598434-B2 | Benzazepine compound | ASTELLAS PHARMA INC. (JP) | 2017-03-21 | — | — | US | disclosed |