Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | CA12 | O43570 | 1/20 | 0.31 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL790105 | 0.87 | TSHR (0.39) | TSHRCA12CA14SMN1; SMN2 | |
| SCHEMBL790359 | 0.87 | TSHR (0.39) | TSHRCA12CA14SMN1; SMN2 | |
| SCHEMBL790024 | 0.87 | TSHR (0.39) | TSHRCA12CA14SMN1; SMN2 | |
| SCHEMBL19764851 | 0.81 | TSHR (0.37) | TSHRCA12 | |
| SCHEMBL784283 | 0.73 | TSHR (0.42) | TSHRCA12CA14SMN1; SMN2 | |
| SCHEMBL784245 | 0.73 | TSHR (0.42) | TSHRCA12CA14SMN1; SMN2 | |
| SCHEMBL25504658 | 0.73 | TSHR (0.42) | TSHRCA12CA14SMN1; SMN2 | |
| SCHEMBL784179 | 0.73 | TSHR (0.42) | TSHRCA12CA14SMN1; SMN2 | |
| SCHEMBL22503374 | 0.72 | — | — | |
| SCHEMBL18879824 | 0.72 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9598457-B2 | Substituted nucleosides, nucleotides and analogs thereof | ALIOS BIOPHARMA, INC. (US) | 2017-03-21 | — | — | US | disclosed |