Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | CA12 | O43570 | 4/20 | 0.40 |
| ▸ | CA1 | P00915 | 4/20 | 0.40 |
| ▸ | CA2 | P00918 | 4/20 | 0.40 |
| ▸ | CA9 | Q16790 | 4/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.33 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | PPARG | P37231 | 1/20 | 0.31 |
| ▸ | NCOA2 | Q15596 | 1/20 | 0.31 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.31 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.31 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.31 |
| ▸ | CA7 | P43166 | 3/20 | 0.30 |
| ▸ | CA14 | Q9ULX7 | 3/20 | 0.30 |
| ▸ | LMNA | P02545 | 2/20 | 0.30 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL784179 | 0.80 | TSHR (0.42) | TSHRCA12CA1CA2CA9 | |
| SCHEMBL784245 | 0.80 | TSHR (0.42) | TSHRCA12CA1CA2CA9 | |
| SCHEMBL784283 | 0.80 | TSHR (0.42) | TSHRCA12CA1CA2CA9 | |
| Hydrochloric Acid SCHEMBL23859870 | 0.78 | TSHR (0.40) | TSHRCA12CA1CA2CA9 | |
| SCHEMBL790359 | 0.76 | TSHR (0.39) | TSHRCA12CA1CA2CA9 | |
| SCHEMBL790024 | 0.76 | TSHR (0.39) | TSHRCA12CA1CA2CA9 | |
| SCHEMBL790105 | 0.76 | TSHR (0.39) | TSHRCA12CA1CA2CA9 | |
| SCHEMBL4585366 | 0.75 | TSHR (0.53) | TSHRCA12CA1CA2CA9 | |
| SCHEMBL19764851 | 0.75 | TSHR (0.37) | TSHRCA12CA1CA2CA9 | |
| SCHEMBL14113868 | 0.73 | TSHR (0.36) | TSHRCA1CA2HCAR2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023078464-A1 | EPSILON-POLY-L-LYSINE-BASED DRUG CONJUGATE, INTERMEDIATE THEREOF, AND APPLICATION THEREOF | 上海弼领生物技术有限公司 | 2023-05-11 | — | — | WO | disclosed |