Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRA3 | P34903 | 15/20 | 0.49 |
| ▸ | GABRG2 | P18507 | 10/20 | 0.49 |
| ▸ | GABRB3 | P28472 | 10/20 | 0.49 |
| ▸ | GABRA2 | P47869 | 12/20 | 0.48 |
| ▸ | GABRA1 | P14867 | 12/20 | 0.48 |
| ▸ | GABRA5 | P31644 | 11/20 | 0.48 |
| ▸ | GABRB2 | P47870 | 8/20 | 0.48 |
| ▸ | GABRA6 | Q16445 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13061673 | 0.75 | GABRA3 (0.81) | GABRA3GABRG2GABRB3GABRA2GABRA1 | |
| SCHEMBL7724596 | 0.73 | GABRA3 (0.63) | GABRA3GABRG2GABRB3GABRA2GABRA1 | |
| SCHEMBL2845763 | 0.73 | GABRA3 (0.72) | GABRA3GABRG2GABRB3GABRA2GABRA1 | |
| SCHEMBL19368515 | 0.66 | GABRA3 (0.84) | GABRA3GABRG2GABRB3GABRA2GABRA1 | |
| SCHEMBL29691961 | 0.66 | GABRA3 (0.84) | GABRA3GABRG2GABRB3GABRA2GABRA1 | |
| SCHEMBL29711927 | 0.66 | GABRA3 (1.00) | GABRA3GABRG2GABRB3GABRA2GABRA1 | |
| SCHEMBL19368516 | 0.66 | GABRA3 (1.00) | GABRA3GABRG2GABRB3GABRA2GABRA1 | |
| SCHEMBL29711999 | 0.64 | GABRA3 (1.00) | GABRA3GABRG2GABRB3GABRA2GABRA1 | |
| SCHEMBL19368517 | 0.64 | GABRA3 (1.00) | GABRA3GABRG2GABRB3GABRA2GABRA1 | |
| SCHEMBL13061808 | 0.64 | GABRA3 (0.82) | GABRA3GABRG2GABRB3GABRA2GABRA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9597342-B2 | GABAergic receptor subtype selective ligands and their uses | UWM RESEARCH FOUNDATION, INC. (US) | 2017-03-21 | — | — | US | disclosed |