SCHEMBL1865

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL2237	0.93	OPRM1 (0.43)	ABCC3ABCC4ABCB11CYP2C8CYP2C9
	SCHEMBL1601	0.92	KCNA3 (0.42)	ABCC3ABCC4ABCB11CYP2C8CYP2C9
	SCHEMBL2663	0.90	LPAR1 (0.43)	TRPV1ABCC3ABCC4ABCB11CYP2C8
	SCHEMBL2379	0.88	KCNA3 (0.38)	TRPV1ABCC3ABCC4ABCB11CYP2C8
	SCHEMBL1603069	0.83	PTPN1 (0.36)	TRPV1ABCC3ABCC4ABCB11CYP2C8
	SCHEMBL1594	0.83	PTPN1 (0.36)	TRPV1ABCC3ABCC4ABCB11CYP2C8
	SCHEMBL2333	0.82	KCNA3 (0.43)	ABCC3ABCC4ABCB11CYP2C8CYP2C9
	SCHEMBL2566	0.82	LPAR1 (0.43)	ABCC3ABCC4ABCB11CYP2C8CYP2C9
	SCHEMBL1695	0.82	LPAR1 (0.49)	ABCC3ABCC4ABCB11CYP2C8CYP2C9
	SCHEMBL2280	0.80	ABCC3 (0.39)	ABCC3ABCC4ABCB11CYP2C8CYP2C9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.