⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20054453 | 0.72 | — | — | |
| SCHEMBL21548060 | 0.72 | — | — | |
| SCHEMBL181825 | 0.64 | — | — | |
| SCHEMBL18611173 | 0.64 | — | — | |
| SCHEMBL20910423 | 0.63 | — | — | |
| SCHEMBL21029488 | 0.63 | — | — | |
| SCHEMBL6887791 | 0.63 | — | — | |
| SCHEMBL24817654 | 0.61 | — | — | |
| SCHEMBL8464111 | 0.61 | — | — | |
| SCHEMBL10119844 | 0.61 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230303514-A1 | TLR7/8 ANTAGONISTS AND USES THEREOF | MERCK PATENT GMBH (DE) | 2023-09-28 | — | — | US | disclosed |
| EP-2572632-B1 | Temperature-adjusted analyte determination for biosensor systems | ASCENSIA DIABETES CARE HOLDINGS AG (CH) | 2020-02-19 | — | — | EP | disclosed |
| CN-109476639-A | Pyrrolidin derivatives | 橘生药品工业股份有限公司 | 2019-03-15 | — | — | CN | disclosed |
| US-9598447-B2 | Phosphorus-substituted quinoxaline-type piperidine compounds and uses thereof | PURDUE PHARMA L.P. (US) | 2017-03-21 | — | — | US | disclosed |