⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6887791 | 1.00 | — | — | |
| SCHEMBL20006636 | 0.73 | — | — | |
| SCHEMBL21369241 | 0.67 | — | — | |
| SCHEMBL2274519 | 0.65 | — | — | |
| SCHEMBL18650010 | 0.63 | — | — | |
| SCHEMBL19245994 | 0.63 | — | — | |
| SCHEMBL20054453 | 0.60 | — | — | |
| SCHEMBL21548060 | 0.60 | — | — | |
| SCHEMBL13442848 | 0.59 | — | — | |
| SCHEMBL12656449 | 0.59 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10668051-B2 | Modulators of calcium release-activated calcium channel | RHIZEN PHARMACEUTICALS SA (CH) | 2020-06-02 | — | — | US | disclosed |
| US-20190160046-A1 | NOVEL MODULATORS OF CALCIUM RELEASE-ACTIVATED CALCIUM CHANNEL | RHIZEN PHARMACEUTICALS AG (CH) | 2019-05-30 | — | — | US | disclosed |