Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE3A | Q14432 | 3/20 | 0.58 |
| ▸ | SLC29A1 | Q99808 | 2/20 | 0.58 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.58 |
| ▸ | LMNA | P02545 | 3/20 | 0.47 |
| ▸ | THRB | P10828 | 1/20 | 0.47 |
| ▸ | MTOR | P42345 | 1/20 | 0.47 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.47 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.47 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.47 |
| ▸ | P2RY2 | P41231 | 5/20 | 0.45 |
| ▸ | SLC28A1 | O00337 | 1/20 | 0.44 |
| ▸ | SLC28A2 | O43868 | 1/20 | 0.44 |
| ▸ | SLC28A3 | Q9HAS3 | 1/20 | 0.44 |
| ▸ | P2RY4 | P51582 | 3/20 | 0.41 |
| ▸ | P2RY6 | Q15077 | 1/20 | 0.41 |
| ▸ | CACNA1F | O60840 | 2/20 | 0.39 |
| ▸ | ALB | P02768 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | CACNA1D | Q01668 | 2/20 | 0.39 |
| ▸ | CACNA1S | Q13698 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL547055 | 0.87 | PDE3A (0.74) | PDE3ASLC29A1PDE4DLMNATHRB | |
| SCHEMBL1880453 | 0.87 | PDE3A (0.74) | PDE3ASLC29A1PDE4DLMNATHRB | |
| SCHEMBL547062 | 0.86 | SLC29A1 (0.57) | PDE3ASLC29A1PDE4DP2RY2SLC28A1 | |
| SCHEMBL17184312 | 0.85 | PDE3A (0.67) | PDE3ASLC29A1PDE4DLMNATHRB | |
| SCHEMBL6271158 | 0.85 | SLC29A1 (0.59) | PDE3ASLC29A1PDE4DP2RY2SLC28A1 | |
| Phosphoric Acid SCHEMBL20769284 | 0.83 | PDE3A (0.68) | PDE3ASLC29A1PDE4DLMNATHRB | |
| Phosphoric Acid SCHEMBL4576226 | 0.83 | PDE3A (0.68) | PDE3ASLC29A1PDE4DLMNATHRB | |
| SCHEMBL1865152 | 0.83 | PDE3A (0.46) | PDE3ASLC29A1PDE4DLMNATHRB | |
| Phosphoric Acid SCHEMBL20769288 | 0.82 | SLC28A1 (0.53) | SLC29A1P2RY2SLC28A1SLC28A2SLC28A3 | |
| Phosphoric Acid SCHEMBL4575970 | 0.82 | SLC28A1 (0.53) | SLC29A1P2RY2SLC28A1SLC28A2SLC28A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010057160-A9 | RELEASABLE FUSOGENIC LIPIDS FOR NUCLEIC ACIDS DELIVERY SYSTEMS | ENZON PHARMACEUTICALS, INC. (US) | 2011-05-05 | — | — | WO | disclosed |