Known targets — ChEMBL curated mechanism
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
The experimentally established mechanism targets of Phosphoric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC28A1 | O00337 | 1/20 | 0.53 |
| ▸ | SLC28A2 | O43868 | 1/20 | 0.53 |
| ▸ | SLC29A1 | Q99808 | 1/20 | 0.53 |
| ▸ | SLC28A3 | Q9HAS3 | 1/20 | 0.53 |
| ▸ | P2RY2 | P41231 | 11/20 | 0.51 |
| ▸ | P2RY4 | P51582 | 5/20 | 0.51 |
| ▸ | POLA1 | P09884 | 1/20 | 0.48 |
| ▸ | P2RY14 | Q15391 | 3/20 | 0.46 |
| ▸ | P2RY6 | Q15077 | 6/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Phosphoric Acid SCHEMBL4575970 | 1.00 | SLC28A1 (0.53) | SLC28A1SLC28A2SLC29A1SLC28A3P2RY2 | |
| SCHEMBL547062 | 0.95 | SLC29A1 (0.57) | SLC28A1SLC28A2SLC29A1SLC28A3P2RY2 | |
| SCHEMBL7027795 | 0.91 | SLC29A1 (0.53) | SLC28A1SLC28A2SLC29A1SLC28A3P2RY2 | |
| Phosphoric Acid SCHEMBL20769291 | 0.86 | SLC28A1 (0.53) | SLC28A1SLC28A2SLC29A1SLC28A3P2RY2 | |
| Phosphoric Acid SCHEMBL4575893 | 0.86 | SLC28A1 (0.53) | SLC28A1SLC28A2SLC29A1SLC28A3P2RY2 | |
| SCHEMBL20769290 | 0.85 | P2RY2 (0.63) | P2RY2P2RY4POLA1P2RY14P2RY6 | |
| SCHEMBL5022511 | 0.85 | SLC28A1 (0.54) | SLC28A1SLC28A2SLC29A1SLC28A3P2RY2 | |
| Phosphoric Acid SCHEMBL21751466 | 0.85 | SLC29A1 (0.55) | SLC28A1SLC28A2SLC29A1SLC28A3P2RY2 | |
| Phosphoramidic Acid SCHEMBL17439381 | 0.84 | SLC29A1 (0.51) | SLC28A1SLC28A2SLC29A1SLC28A3P2RY2 | |
| Phosphoric Acid SCHEMBL21489124 | 0.84 | SLC28A1 (0.51) | SLC28A1SLC28A2SLC29A1SLC28A3P2RY2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10633663-B2 | Therapeutic strategies for ovarian cancer: AMHR2-RNA aptamer | UNIVERSITY OF CINCINNATI (US) | 2020-04-28 | — | — | US | disclosed |
| US-20190071674-A1 | THERAPEUTIC STRATEGIES FOR OVARIAN CANCER: AMHR2-RNA APTAMER | UNIVERSITY OF CINCINNATI | 2019-03-07 | — | — | US | disclosed |