Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2D6 | P10635 | 1/20 | 0.60 |
| ▸ | THRB | P10828 | 1/20 | 0.60 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.60 |
| ▸ | TSHR | P16473 | 1/20 | 0.58 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.58 |
| ▸ | FYN | P06241 | 1/20 | 0.58 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.58 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.58 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.58 |
| ▸ | DRD4 | P21917 | 1/20 | 0.58 |
| ▸ | DRD3 | P35462 | 1/20 | 0.58 |
| ▸ | CA2 | P00918 | 12/20 | 0.57 |
| ▸ | CA12 | O43570 | 11/20 | 0.57 |
| ▸ | CA1 | P00915 | 11/20 | 0.57 |
| ▸ | CA9 | Q16790 | 6/20 | 0.57 |
| ▸ | PKM | P14618 | 1/20 | 0.52 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.52 |
| ▸ | CA4 | P22748 | 7/20 | 0.50 |
| ▸ | CA5A | P35218 | 7/20 | 0.50 |
| ▸ | CA7 | P43166 | 7/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1582590 | 1.00 | CYP2D6 (0.60) | CYP2D6THRBHSD17B10TSHRNR3C1 | |
| SCHEMBL133580 | 1.00 | CYP2D6 (0.60) | CYP2D6THRBHSD17B10TSHRNR3C1 | |
| SCHEMBL13465295 | 1.00 | CYP2D6 (0.60) | CYP2D6THRBHSD17B10TSHRNR3C1 | |
| SCHEMBL3188307 | 1.00 | CYP2D6 (0.60) | CYP2D6THRBHSD17B10TSHRNR3C1 | |
| SCHEMBL18880355 | 1.00 | CYP2D6 (0.60) | CYP2D6THRBHSD17B10TSHRNR3C1 | |
| SCHEMBL12569416 | 1.00 | CYP2D6 (0.60) | CYP2D6THRBHSD17B10TSHRNR3C1 | |
| SCHEMBL133581 | 1.00 | CYP2D6 (0.60) | CYP2D6THRBHSD17B10TSHRNR3C1 | |
| SCHEMBL1140728 | 1.00 | CYP2D6 (0.60) | CYP2D6THRBHSD17B10TSHRNR3C1 | |
| SCHEMBL22766232 | 1.00 | CYP2D6 (0.60) | CYP2D6THRBHSD17B10TSHRNR3C1 | |
| SCHEMBL17119468 | 1.00 | CYP2D6 (0.60) | CYP2D6THRBHSD17B10TSHRNR3C1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2627691-B1 | DEGRADABLE POLYCARBONATES | TEXAS A&M UNIV (US) | 2020-11-25 | — | — | EP | disclosed |
| WO-2017046535-A1 | MULTI-FUNCTIONALIZED POLYSACCHARIDE COMPOUNDS AND USE THEREOF FOR TARGETING THE CATION-INDEPENDENT MANNOSE 6-PHOSPHATE RECEPTOR | NANOMEDSYN (FR) | 2017-03-23 | — | — | WO | disclosed |