Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2D6 | P10635 | 1/20 | 0.60 |
| ▸ | THRB | P10828 | 1/20 | 0.60 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.60 |
| ▸ | TSHR | P16473 | 1/20 | 0.58 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.58 |
| ▸ | FYN | P06241 | 1/20 | 0.58 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.58 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.58 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.58 |
| ▸ | DRD4 | P21917 | 1/20 | 0.58 |
| ▸ | DRD3 | P35462 | 1/20 | 0.58 |
| ▸ | CA2 | P00918 | 12/20 | 0.57 |
| ▸ | CA12 | O43570 | 11/20 | 0.57 |
| ▸ | CA1 | P00915 | 11/20 | 0.57 |
| ▸ | CA9 | Q16790 | 6/20 | 0.57 |
| ▸ | PKM | P14618 | 1/20 | 0.52 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.52 |
| ▸ | CA4 | P22748 | 7/20 | 0.50 |
| ▸ | CA5A | P35218 | 7/20 | 0.50 |
| ▸ | CA7 | P43166 | 7/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1582590 | 1.00 | CYP2D6 (0.60) | CYP2D6THRBHSD17B10TSHRNR3C1 | |
| SCHEMBL133580 | 1.00 | CYP2D6 (0.60) | CYP2D6THRBHSD17B10TSHRNR3C1 | |
| SCHEMBL18652541 | 1.00 | CYP2D6 (0.60) | CYP2D6THRBHSD17B10TSHRNR3C1 | |
| SCHEMBL13465295 | 1.00 | CYP2D6 (0.60) | CYP2D6THRBHSD17B10TSHRNR3C1 | |
| SCHEMBL3188307 | 1.00 | CYP2D6 (0.60) | CYP2D6THRBHSD17B10TSHRNR3C1 | |
| SCHEMBL18880355 | 1.00 | CYP2D6 (0.60) | CYP2D6THRBHSD17B10TSHRNR3C1 | |
| SCHEMBL12569416 | 1.00 | CYP2D6 (0.60) | CYP2D6THRBHSD17B10TSHRNR3C1 | |
| SCHEMBL133581 | 1.00 | CYP2D6 (0.60) | CYP2D6THRBHSD17B10TSHRNR3C1 | |
| SCHEMBL1140728 | 1.00 | CYP2D6 (0.60) | CYP2D6THRBHSD17B10TSHRNR3C1 | |
| SCHEMBL22766232 | 1.00 | CYP2D6 (0.60) | CYP2D6THRBHSD17B10TSHRNR3C1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170233429-A1 | THIONUCLEOSIDE DERIVATIVE OR SALT THEREOF, AND PHARMACEUTICAL COMPOSITION | FUJIFILM CORPORATION (JP) | 2017-08-17 | — | — | US | disclosed |
| US-20170175151-A1 | NOVEL MATERIALS DERIVED FROM FERMENTATION-PRODUCED RHAMNOLIPIDS AND METHODS OF PRODUCTION | THE UNIVERSITY OF AKRON | 2017-06-22 | — | — | US | disclosed |
| US-9663551-B2 | Solanidine-derived compounds | Université de Picardie Jules Verne (FR) | 2017-05-30 | — | — | US | disclosed |
| US-20160152659-A1 | NOVEL SOLANIDINE-DERIVED COMPOUNDS | SEMENCES INNOVATION PROTECTION RECHERCHE ET ENVIROMENT (FR) | 2016-06-02 | — | — | US | disclosed |
| WO-2015143169-A1 | NOVEL MATERIALS DERIVED FROM FERMENTATION-PRODUCED RHAMNOLIPIDS | THE UNIVERSITY OF AKRON (US) | 2015-09-24 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160152659-A1 | NOVEL SOLANIDINE-DERIVED COMPOUNDS | STOM, PNMT, SEPTIN9 | CYP2D6 3252/4885THRB 3668/4885HSD17B10 4699/4885 |
| US-20170175151-A1 | NOVEL MATERIALS DERIVED FROM FERMENTATION-PRODUCED RHAMNOLIPIDS AND METHODS OF PRODUCTION | HACL2, COASY, FASN | CYP2D6 3081/4885THRB 3512/4885HSD17B10 39/4885 |
| US-20170233429-A1 | THIONUCLEOSIDE DERIVATIVE OR SALT THEREOF, AND PHARMACEUTICAL COMPOSITION | SLC11A2, RNASE1, TYMP | CYP2D6 2481/4885THRB 2449/4885HSD17B10 687/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.