SCHEMBL186528

SCHEMBL186528

CC(O)N(CC(=O)O)C(C)O

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 2/20 0.39
EYA2 O00167 1/20 0.39
APP P05067 1/20 0.39
ACE P12821 1/20 0.39
TP53 P04637 1/20 0.38
KDM4E B2RXH2 1/20 0.38
LMNA P02545 1/20 0.38
CHRM2 P08172 1/20 0.38
ADRA2A P08913 1/20 0.38
ALOX15 P16050 1/20 0.38
TSHR P16473 1/20 0.38
DRD1 P21728 1/20 0.38
SLC6A2 P23975 1/20 0.38
SLC6A4 P31645 1/20 0.38
CYP2C19 P33261 1/20 0.38
ADRA1A P35348 1/20 0.38
DRD3 P35462 1/20 0.38
BLM P54132 1/20 0.38
PMP22 Q01453 1/20 0.38
SLC6A3 Q01959 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1322891 0.97 TDP1 (0.38) TDP1EYA2APPACETP53
SCHEMBL11295988 0.97 TDP1 (0.38) TDP1EYA2APPACETP53
Ammonia Solution, Strong SCHEMBL3916100 0.97 TDP1 (0.38) TDP1EYA2APPACETP53
SCHEMBL3901854 0.97 TDP1 (0.38) TDP1EYA2APPACETP53
Acetic Acid SCHEMBL10723799 0.80
SCHEMBL22128524 0.80 TP53 (0.33) TDP1EYA2APPACETP53
SCHEMBL867976 0.80 TDP1 (0.41) TDP1EYA2APPACETP53
SCHEMBL16057464 0.79 TDP1 (0.36) TDP1EYA2APPACETP53
SCHEMBL8998280 0.79 TDP1 (0.36) TDP1EYA2APPACETP53
SCHEMBL8700152 0.79 TDP1 (0.58) TDP1EYA2APPACETP53

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 848 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260048155-A1 BIOCOMPATIBLE PARAHYDROGEN HYPERPOLARIZED SOLUTIONS BY PRECIPITATION AND RE-DISSOLUTION UNIV NORTH CAROLINA STATE (US) 2026-02-19 US claimed
US-20240392009-A1 PHARMACEUTICAL COMPOSITIONS FOR ANTIBODIES AND MAKING AND USING THE SAME INVETX INC (US) 2024-11-28 US claimed
US-12083117-B2 Compositions and kits useful for treatment of respiratory illness THE PROCTER & GAMBLE COMPANY (US) 2024-09-10 US claimed
WO-2024044520-A1 BIOCOMPATIBLE PARAHYDROGEN HYPERPOLARIZED SOLUTIONS BY PRECIPITATION AND RE-DISSOLUTION NORTH CAROLINA STATE UNIVERSITY (US) 2024-02-29 WO claimed
US-20230414760-A1 PHARMACEUTICAL FORMULATION ASTRAZENECA UK LIMITED (GB) 2023-12-28 US claimed
US-20230364026-A1 STABILIZED SOLID NANOPARTICLE FORMULATIONS OF CANNABINOIDS AND CANNABINOID ANALOGS WITH REDUCED OSTWALD RIPENING FOR ORAL, INHALATION, NASAL AND PARENTERAL DRUG DELIVERY AUSTIN BIOSCIENCES CORP. 2023-11-16 US claimed
EP-4243780-A1 PHARMACEUTICAL FORMULATION AstraZeneca UK Limited (GB) 2023-09-20 EP claimed
EP-4213809-A1 STABILIZED SOLID NANOPARTICLE FORMULATIONS OF CANNABINOIDS AND CANNABINOID ANALOGS WITH REDUCED OSTWALD RIPENING FOR ORAL, INHALATION, NASAL AND PARENTERAL DRUG DELIVERY Luminus Biosciences Inc. (US) 2023-07-26 EP claimed
US-20220370623-A1 Nanoparticles Comprising Prodrugs Stabilized by Albumin for Treatment of Cancer and Other Diseases AUSTIN BIOSCIENCES CORP. 2022-11-24 US claimed
EP-4054550-A2 NANOPARTICLES COMPRISING PRODRUGS STABILIZED BY ALBUMIN FOR TREATMENT OF CANCER AND OTHER DISEASES Luminus Biosciences Inc. (US) 2022-09-14 EP claimed
US-5693517-A RNA TEMPLATE, DNA POLYMERASE, PRIMER, NUCLEOSIDE TRIPHOSPHATES, DIVALENT AND MONOVALENT CATIONS, BUFFERING AGENT ROCHE MOLECULAR SYSTEMS, INC. (US) 1997-12-02 US claimed
EP-0395346-B1 Photosensitive composition FUJI PHOTO FILM CO LTD (JP) 1996-11-27 EP claimed
US-5561058-A AMPLIFYING RNA TARGETS HOFFMANN-LA ROCHE INC. (US) 1996-10-01 US claimed
US-5019133-A Method for dyeing polyester-containing fibers in an alkaline dyeing bath and dyeing assistant, an amino-acid compound MITSUBISHI KASEI CORPORATION (JP) 1991-05-28 US claimed
EP-0096654-B1 PROCESS FOR SIZING PAPER WITH ANIONIC, HYDROPHOBIC SIZING AGENTS AND CATIONIC RETENTION AGENTS CIBA-GEIGY AG (CH) 1987-10-28 EP claimed
EP-0158556-B1 PROCESS FOR THE PREPARATION OF HYDROXYALKYLAMINOACETIC ACIDS SOCIETE FRANCAISE HOECHST Société anonyme dite: (FR) 1987-07-01 EP claimed
EP-0158556-A1 Process for the preparation of hydroxyalkylaminoacetic acids SOCIETE FRANCAISE HOECHST Société anonyme dite: (FR) 1985-10-16 EP claimed
EP-0096654-A2 Process for sizing paper with anionic, hydrophobic sizing agents and cationic retention agents CIBA-GEIGY AG (CH) 1983-12-21 EP claimed
US-4297100-A Aqueous dye preparations CIBA-GEIGY CORPORATION (US) 1981-10-27 US claimed
US-4192722-A Composition and method for stannate plating of large aluminum parts REYNOLDS METALS COMPANY (US) 1980-03-11 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260048155-A1 BIOCOMPATIBLE PARAHYDROGEN HYPERPOLARIZED SOLUTIONS BY PRECIPITATION AND RE-DISSOLUTION HNRNPR, SIGMAR1, MAP2K1 TDP1 3286/4885EYA2 1885/4885APP 1140/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.