Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GJB2 | P29033 | 4/20 | 0.50 |
| ▸ | GBA1 | P04062 | 3/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | IGF2R | P11717 | 4/20 | 0.40 |
| ▸ | TNF | P01375 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | LGALS8 | O00214 | 1/20 | 0.36 |
| ▸ | LGALS3 | P17931 | 1/20 | 0.36 |
| ▸ | LGALS4 | P56470 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18653473 | 1.00 | GJB2 (0.50) | GJB2GBA1MAPK1IGF2RTNF | |
| SCHEMBL8686677 | 0.96 | GBA1 (0.53) | GJB2GBA1MAPK1IGF2RTNF | |
| SCHEMBL8691523 | 0.96 | GBA1 (0.53) | GJB2GBA1MAPK1IGF2RTNF | |
| SCHEMBL8686418 | 0.96 | GBA1 (0.53) | GJB2GBA1MAPK1IGF2RTNF | |
| SCHEMBL8686417 | 0.96 | GBA1 (0.53) | GJB2GBA1MAPK1IGF2RTNF | |
| SCHEMBL28296339 | 0.92 | GBA1 (0.51) | GJB2GBA1MAPK1IGF2RTNF | |
| SCHEMBL18412556 | 0.91 | GJB2 (0.48) | GJB2GBA1MAPK1IGF2RTNF | |
| SCHEMBL13760997 | 0.91 | GJB2 (0.47) | GJB2GBA1MAPK1IGF2RTNF | |
| SCHEMBL19682306 | 0.89 | GJB2 (0.49) | GJB2GBA1MAPK1IGF2RTNF | |
| SCHEMBL16381103 | 0.87 | GJB2 (0.56) | GJB2GBA1MAPK1TNF |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017046172-A1 | CARBOHYDRATE LIGANDS THAT BIND TO ANTIBODIES AGAINST GLYCOEPITOPES OF GLYCOSPHINGOLIPIDS | UNIVERSITÄT BASEL (CH) | 2017-03-23 | — | — | WO | disclosed |