Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSK3B | P49841 | 12/20 | 0.86 |
| ▸ | FLT3 | P36888 | 7/20 | 0.71 |
| ▸ | KDR | P35968 | 11/20 | 0.69 |
| ▸ | QPCT | Q16769 | 1/20 | 0.51 |
| ▸ | CAMK2D | Q13557 | 3/20 | 0.49 |
| ▸ | PLK4 | O00444 | 1/20 | 0.47 |
| ▸ | AURKA | O14965 | 1/20 | 0.47 |
| ▸ | SRC | P12931 | 1/20 | 0.47 |
| ▸ | FLT4 | P35916 | 1/20 | 0.47 |
| ▸ | TEK | Q02763 | 1/20 | 0.47 |
| ▸ | PTK2 | Q05397 | 1/20 | 0.47 |
| ▸ | PRKCA | P17252 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18655375 | 0.93 | GSK3B (0.79) | GSK3BFLT3KDRQPCTCAMK2D | |
| SCHEMBL10069744 | 0.92 | GSK3B (1.00) | GSK3BFLT3KDRQPCTCAMK2D | |
| SCHEMBL9954914 | 0.88 | GSK3B (0.87) | GSK3BFLT3KDRQPCTCAMK2D | |
| SCHEMBL18655374 | 0.88 | GSK3B (0.87) | GSK3BFLT3KDRQPCTPLK4 | |
| SCHEMBL10070566 | 0.87 | GSK3B (0.75) | GSK3BFLT3KDRQPCTCAMK2D | |
| SCHEMBL18655376 | 0.85 | GSK3B (0.76) | GSK3BFLT3KDRQPCTPLK4 | |
| SCHEMBL18655372 | 0.84 | GSK3B (0.80) | GSK3BFLT3KDRQPCTCAMK2D | |
| SCHEMBL9955798 | 0.83 | GSK3B (1.00) | GSK3BFLT3KDRQPCTCAMK2D | |
| SCHEMBL10070111 | 0.82 | GSK3B (0.68) | GSK3BFLT3KDRQPCTCAMK2D | |
| SCHEMBL18628480 | 0.82 | GSK3B (0.68) | GSK3BFLT3KDRQPCTCAMK2D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2655359-B1 | CONJUGATED 3-(INDOLYL)- AND 3-(AZAINDOLYL)-4-ARYLMALEIMIDE COMPOUNDS AND THEIR USE IN TUMOR TREATMENT | Johannes-Gutenberg-Universität Mainz (DE) | 2017-03-22 | — | — | EP | disclosed |