Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSL | P07711 | 1/20 | 0.59 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.59 |
| ▸ | CPB1 | P15086 | 1/20 | 0.57 |
| ▸ | CPB2 | Q96IY4 | 1/20 | 0.57 |
| ▸ | FOLH1 | Q04609 | 3/20 | 0.56 |
| ▸ | CA1 | P00915 | 1/20 | 0.53 |
| ▸ | CA2 | P00918 | 1/20 | 0.53 |
| ▸ | MMP2 | P08253 | 1/20 | 0.51 |
| ▸ | MMP9 | P14780 | 1/20 | 0.51 |
| ▸ | ANPEP | P15144 | 1/20 | 0.50 |
| ▸ | PTGER4 | P35408 | 3/20 | 0.49 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17073781 | 0.88 | CTSL (0.63) | CTSLSIRT2CPB1CPB2FOLH1 | |
| Hydrochloric Acid SCHEMBL30340169 | 0.88 | SIRT2 (0.60) | CTSLSIRT2CPB1CPB2FOLH1 | |
| SCHEMBL18659611 | 0.88 | CTSL (0.66) | CTSLSIRT2CPB1CPB2FOLH1 | |
| SCHEMBL17073778 | 0.84 | CTSL (0.64) | CTSLSIRT2 | |
| SCHEMBL16869913 | 0.84 | ANPEP (0.61) | CTSLSIRT2CPB1CPB2FOLH1 | |
| SCHEMBL22674651 | 0.83 | FOLH1 (0.60) | SIRT2CPB1CPB2FOLH1CA1 | |
| SCHEMBL20794742 | 0.83 | ANPEP (0.60) | CTSLSIRT2CPB1CPB2FOLH1 | |
| SCHEMBL18659633 | 0.83 | CTSL (0.62) | CTSLSIRT2CPB1CPB2FOLH1 | |
| SCHEMBL30340359 | 0.83 | MAPT (0.60) | CTSLSIRT2CPB1CPB2FOLH1 | |
| SCHEMBL14194799 | 0.83 | HTT (0.59) | SIRT2CPB1CPB2FOLH1MMP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170081363-A1 | PHARMACEUTICALLY RELEVANT AROMATIC-CATIONIC PEPTIDES | STEALTH BIOTHERAPEUTICS CORP (MC) | 2017-03-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170081363-A1 | PHARMACEUTICALLY RELEVANT AROMATIC-CATIONIC PEPTIDES | ADM2, VIP, ANPEP | CTSL 200/4885SIRT2 2787/4885CPB1 563/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.