Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21891922 | 0.77 | FGFR1 (0.34) | FGFR1 | |
| SCHEMBL18655973 | 0.75 | ACVR1 (0.33) | FGFR1 | |
| SCHEMBL18650823 | 0.70 | FGFR1 (0.36) | FGFR1 | |
| SCHEMBL21846654 | 0.68 | FGFR1 (0.30) | FGFR1 | |
| SCHEMBL21846656 | 0.65 | GBA1 (0.31) | — | |
| SCHEMBL25363257 | 0.63 | — | — | |
| SCHEMBL10563056 | 0.63 | — | — | |
| SCHEMBL10563065 | 0.63 | — | — | |
| SCHEMBL7973427 | 0.63 | — | — | |
| SCHEMBL179075 | 0.60 | GAA (0.34) | FGFR1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170081317-A1 | HETEROARYL COMPOUNDS AS IRAK INHIBITORS AND USES THEREOF | MERCK PATENT GMBH (DE) | 2017-03-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170081317-A1 | HETEROARYL COMPOUNDS AS IRAK INHIBITORS AND USES THEREOF | IRAK2, IRAK3, IRAK1 | FGFR1 1134/4885GAA 1757/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.