⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16190280 | 0.77 | — | — | |
| SCHEMBL1524638 | 0.77 | — | — | |
| SCHEMBL20158391 | 0.74 | — | — | |
| SCHEMBL25363257 | 0.71 | — | — | |
| SCHEMBL10563056 | 0.71 | — | — | |
| SCHEMBL10563065 | 0.71 | — | — | |
| SCHEMBL27391944 | 0.69 | APEX1 (0.31) | — | |
| SCHEMBL30988189 | 0.69 | CHRNB2 (0.33) | — | |
| SCHEMBL24909954 | 0.68 | — | — | |
| SCHEMBL11523135 | 0.68 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001072704-A1 | AZETIDINONE DERIVATIVES, A PROCESS FOR THEIR PREPARATION AND A METHOD FOR PRODUCING 1-β-ALKYL AZETIDINONE USING THE SAME | DAEWOONG PHARMACEUTICAL CO., LTD. (KR) | 2001-10-04 | — | — | WO | disclosed |
| EP-0294934-B1 | Diastereomeric 5R,6S-6-(1R-hydroxyethyl)-2-(cis-1-oxo-3-thiolanylthio)-2-penem-3-carboxylic acids | PFIZER (US) | 1996-01-10 | — | — | EP | disclosed |
| US-5191077-A | Diastereomeric 5R,6S-6-(1R-hydroxyethyl)-2-(cis-1-oxo-3-thiolanylthio)-2-penem-3-carboxylic acids | PFIZER INC. (US) | 1993-03-02 | — | — | US | disclosed |
| US-5013729-A | Diastereomeric 5R,6S-6-(1R-hydroxyethyl)-2-(cis-1-oxo-3-thiolanylthio)-2-penem-3-carboxylic acids | PFIZER INC. (US) | 1991-05-07 | — | — | US | disclosed |
| EP-0294934-A2 | Diastereomeric 5R,6S-6-(1R-hydroxyethyl)-2-(cis-1-oxo-3-thiolanylthio)-2-penem-3-carboxylic acids | PFIZER INC. (US) | 1988-12-14 | — | — | EP | disclosed |