Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 2/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.46 |
| ▸ | NPC1 | O15118 | 3/20 | 0.39 |
| ▸ | RAB9A | P51151 | 3/20 | 0.39 |
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | ACE | P12821 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | ESR1 | P03372 | 1/20 | 0.38 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.38 |
| ▸ | TNF | P01375 | 1/20 | 0.36 |
| ▸ | NOD1 | Q9Y239 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 3/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | ACHE | P22303 | 2/20 | 0.34 |
| ▸ | BCHE | P06276 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21241111 | 0.89 | CYP1A2 (0.42) | CYP1A2CYP3A4CYP2D6CYP2C19NPC1 | |
| SCHEMBL24108926 | 0.83 | CYP1A2 (0.45) | CYP1A2CYP3A4CYP2D6CYP2C19NPC1 | |
| SCHEMBL20432633 | 0.81 | CYP1A2 (0.44) | CYP1A2CYP3A4CYP2D6CYP2C19NPC1 | |
| SCHEMBL29190942 | 0.79 | CYP3A4 (0.45) | CYP1A2CYP3A4CYP2D6CYP2C19MAPT | |
| SCHEMBL31371688 | 0.76 | ESR1 (0.61) | CYP1A2CYP3A4CYP2D6CYP2C19NPC1 | |
| SCHEMBL311076 | 0.76 | ESR1 (0.61) | CYP1A2CYP3A4CYP2D6CYP2C19NPC1 | |
| SCHEMBL30876036 | 0.76 | ESR1 (0.61) | CYP1A2CYP3A4CYP2D6CYP2C19NPC1 | |
| SCHEMBL29380988 | 0.76 | PTGS1 (0.45) | CYP1A2CYP3A4CYP2D6CYP2C19NPC1 | |
| SCHEMBL311370 | 0.76 | PTGS1 (0.45) | CYP1A2CYP3A4CYP2D6CYP2C19NPC1 | |
| SCHEMBL29597103 | 0.76 | PTGS1 (0.45) | CYP1A2CYP3A4CYP2D6CYP2C19NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20200392331-A1 | POLYCARBONATE COPOLYMER BLENDS, ARTICLES FORMED THEREFROM, AND METHODS OF MANUFACTURE | SHPP GLOBAL TECHNOLOGIES B.V. (NL) | 2020-12-17 | — | — | US | disclosed |
| US-10377860-B2 | Polyetherimides, methods of manufacture, and articles formed therefrom | SABIC GLOBAL TECHNOLOGIES B.V. (NL) | 2019-08-13 | — | — | US | disclosed |
| US-10329421-B2 | Polycarbonate compositions, method of manufacture thereof, and articles therefrom | SABIC GLOBAL TECHNOLOGIES B.V. (NL) | 2019-06-25 | — | — | US | disclosed |
| US-20180086548-A1 | ROUNDED EXTERIOR DIAMETER ADJUSTABLE SHIPPING CONTAINER, SYSTEM, AND METHOD FOR SHIPPING FREIGHT WITH THE CONTAINER MADE OF REINFORCED THERMOPLASTIC FIBER, ARTICLES, COMPOSITIONS FOR THE MANUFACTURE OF THE ARTICLES, METHODS OF MANUFACTURE, AND ARTICLES FORMED THEREFROM | HEATH STEPHAN D (US) | 2018-03-29 | — | — | US | disclosed |
| US-20170086285-A1 | CIRCUIT ASSEMBLIES AND METHOD OF MANUFACTURE THEREOF | SABIC GLOBAL TECHNOLOGIES B.V. (NL) | 2017-03-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10377860-B2 | Polyetherimides, methods of manufacture, and articles formed therefrom | PBRM1, WEE1, WASF2 | CYP1A2 1016/4885CYP3A4 617/4885CYP2D6 472/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.