SCHEMBL29597103

SCHEMBL29597103

Cc1ccc(CCc2ccc(C)c(C)c2)cc1C

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PTGS1 P23219 1/20 0.45
PTGS2 P35354 1/20 0.45
SKP2 Q13309 1/20 0.45
ALDH1A1 P00352 1/20 0.43
ESR1 P03372 1/20 0.42
ESR2 Q92731 1/20 0.42
CNR1 P21554 1/20 0.42
LMNA P02545 2/20 0.39
HTT P42858 1/20 0.39
NPC1 O15118 2/20 0.38
MAPT P10636 2/20 0.38
RAB9A P51151 2/20 0.38
CYP1A2 P05177 2/20 0.38
CYP3A4 P08684 2/20 0.38
CYP2D6 P10635 2/20 0.38
CYP2C19 P33261 2/20 0.38
L3MBTL1 Q9Y468 1/20 0.38
CYP2C9 P11712 1/20 0.38
DAO P14920 2/20 0.38
SLC6A2 P23975 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL311370 1.00 PTGS1 (0.45) PTGS1PTGS2SKP2ALDH1A1ESR1
SCHEMBL29380988 1.00 PTGS1 (0.45) PTGS1PTGS2SKP2ALDH1A1ESR1
SCHEMBL13580008 0.88 PTGS1 (0.42) PTGS1PTGS2SKP2ALDH1A1ESR1
SCHEMBL8077401 0.88 PTGS1 (0.42) PTGS1PTGS2SKP2ALDH1A1ESR1
SCHEMBL2551561 0.88 MAOA (0.48) PTGS1PTGS2ALDH1A1CYP1A2CYP3A4
SCHEMBL598650 0.87 CNR1 (0.50) SKP2ALDH1A1ESR1ESR2CNR1
SCHEMBL31556195 0.87 SKP2 (0.50) PTGS1PTGS2SKP2ALDH1A1ESR1
SCHEMBL21399414 0.86 DAO (0.54) PTGS1PTGS2SKP2ALDH1A1CNR1
SCHEMBL6480325 0.86 GFER (0.61) SKP2ALDH1A1CYP3A4
SCHEMBL8062818 0.86 PTGS1 (0.37) PTGS1PTGS2SKP2ALDH1A1ESR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116200962-A Dispersing agent, coating liquid composition, and thermosensitive recording medium 星光PMC株式会社 2023-06-02 CN disclosed
CN-114507109-A Method for synthesizing bibenzyl compound through photocatalysis 苏州大学张家港工业技术研究院 2022-05-17 CN disclosed