Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.60 |
| ▸ | POLB | P06746 | 1/20 | 0.56 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.55 |
| ▸ | PKM | P14618 | 2/20 | 0.53 |
| ▸ | MAPT | P10636 | 5/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.52 |
| ▸ | GAA | P10253 | 1/20 | 0.52 |
| ▸ | LMNA | P02545 | 2/20 | 0.51 |
| ▸ | ABL1 | P00519 | 1/20 | 0.51 |
| ▸ | HPGD | P15428 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | GALR3 | O60755 | 1/20 | 0.49 |
| ▸ | NR2F2 | P24468 | 1/20 | 0.49 |
| ▸ | RAB9A | P51151 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 2/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23207522 | 0.86 | KDM4E (0.62) | KDM4EPOLBL3MBTL1PKMMAPT | |
| SCHEMBL16238574 | 0.84 | KDM4E (0.60) | KDM4EPOLBL3MBTL1PKMMAPT | |
| SCHEMBL30582921 | 0.84 | KDM4E (0.60) | KDM4EPOLBL3MBTL1PKMMAPT | |
| SCHEMBL18656568 | 0.82 | KDM4E (0.60) | KDM4EPOLBL3MBTL1PKMMAPT | |
| SCHEMBL26785215 | 0.79 | OGA (0.58) | KDM4EPOLBL3MBTL1PKMMAPT | |
| SCHEMBL22984345 | 0.79 | HRH3 (0.59) | KDM4EPOLBL3MBTL1PKMMAPT | |
| SCHEMBL30582924 | 0.79 | KDM4E (0.55) | KDM4EPOLBL3MBTL1PKMMAPT | |
| SCHEMBL5623553 | 0.79 | KDM4E (0.59) | KDM4EPOLBL3MBTL1PKMMAPT | |
| SCHEMBL8082196 | 0.78 | SMN1; SMN2 (0.62) | KDM4EPOLBL3MBTL1MAPTSMN1; SMN2 | |
| SCHEMBL3074677 | 0.78 | KDM4E (0.71) | KDM4EPOLBL3MBTL1PKMMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017049321-A1 | BENZYL AMINE-CONTAINING HETEROCYCLIC COMPOUNDS AND COMPOSITIONS USEFUL AGAINST MYCOBACTERIAL INFECTION | MILLER MARVIN J (US) | 2017-03-23 | — | — | WO | disclosed |