Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.60 |
| ▸ | POLB | P06746 | 1/20 | 0.59 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.57 |
| ▸ | MAPT | P10636 | 4/20 | 0.55 |
| ▸ | GAA | P10253 | 1/20 | 0.55 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.55 |
| ▸ | HPGD | P15428 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.53 |
| ▸ | MEN1 | O00255 | 1/20 | 0.53 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.53 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.53 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.53 |
| ▸ | PKM | P14618 | 2/20 | 0.53 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.52 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.52 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.52 |
| ▸ | ABL1 | P00519 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | SMO | Q99835 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8082196 | 0.94 | SMN1; SMN2 (0.62) | KDM4EPOLBSMN1; SMN2MAPTGAA | |
| SCHEMBL14349623 | 0.87 | KDM4E (0.48) | KDM4EPOLBSMN1; SMN2MAPTL3MBTL1 | |
| SCHEMBL23207522 | 0.86 | KDM4E (0.62) | KDM4EPOLBSMN1; SMN2MAPTGAA | |
| SCHEMBL16238574 | 0.84 | KDM4E (0.60) | KDM4EPOLBSMN1; SMN2MAPTGAA | |
| SCHEMBL30582921 | 0.84 | KDM4E (0.60) | KDM4EPOLBSMN1; SMN2MAPTGAA | |
| SCHEMBL18656554 | 0.82 | KDM4E (0.60) | KDM4EPOLBSMN1; SMN2MAPTGAA | |
| SCHEMBL26785215 | 0.82 | OGA (0.58) | KDM4EPOLBSMN1; SMN2MAPTGAA | |
| SCHEMBL22984345 | 0.82 | HRH3 (0.59) | KDM4EPOLBSMN1; SMN2MAPTGAA | |
| SCHEMBL2155799 | 0.80 | KDM4E (0.74) | KDM4EPOLBSMN1; SMN2MAPTGAA | |
| SCHEMBL2733014 | 0.80 | SMN1; SMN2 (0.50) | KDM4EPOLBSMN1; SMN2MAPTGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017049321-A1 | BENZYL AMINE-CONTAINING HETEROCYCLIC COMPOUNDS AND COMPOSITIONS USEFUL AGAINST MYCOBACTERIAL INFECTION | MILLER MARVIN J (US) | 2017-03-23 | — | — | WO | disclosed |