SCHEMBL1865682

SCHEMBL1865682

COC(=O)C[C@@H](CO[Si](C)(C)C)O[Si](C)(C)C

nearest known ligand 0.33

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
TSHR P16473 3/20 0.33
HSD17B10 Q99714 1/20 0.31
MGAM O43451 1/20 0.31
GAA P10253 1/20 0.31
SI P14410 1/20 0.31
MGAM2 Q2M2H8 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4149922 0.81 LMNA (0.34)
SCHEMBL4149930 0.81 LMNA (0.34)
SCHEMBL16291265 0.76
SCHEMBL16291264 0.76
SCHEMBL19970501 0.73 CYP2D6 (0.41)
SCHEMBL19970503 0.73 CYP2D6 (0.41)
SCHEMBL8854964 0.73
SCHEMBL10375704 0.71
SCHEMBL10012427 0.69 TSHR (0.36) TSHRHSD17B10MGAMGAASI
SCHEMBL20483122 0.69

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7935835-B2 Substituted cycloalkene derivative DAIICHI SANKYO COMPANY, LIMITED (JP) 2011-05-03 US disclosed