Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALK | Q9UM73 | 9/20 | 0.48 |
| ▸ | EGFR | P00533 | 8/20 | 0.46 |
| ▸ | LRRK2 | Q5S007 | 3/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17196875 | 0.91 | EGFR (0.51) | ALKEGFRLRRK2 | |
| SCHEMBL18657447 | 0.85 | EGFR (0.55) | ALKEGFR | |
| SCHEMBL17196873 | 0.79 | EGFR (0.55) | ALKEGFRLRRK2 | |
| SCHEMBL17196683 | 0.77 | EGFR (0.65) | ALKEGFR | |
| SCHEMBL18563173 | 0.75 | EGFR (0.55) | ALKEGFR | |
| SCHEMBL17196871 | 0.75 | EGFR (0.46) | ALKEGFRLRRK2 | |
| SCHEMBL17196684 | 0.75 | EGFR (0.66) | EGFR | |
| SCHEMBL18563178 | 0.73 | EGFR (0.61) | EGFR | |
| Formic Acid SCHEMBL18549295 | 0.73 | EGFR (0.64) | EGFR | |
| SCHEMBL17196834 | 0.71 | EGFR (0.66) | EGFR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3144292-B1 | 2,3,4,6-TETRA-SUBSTITUTED BENZENE-1,5-DIAMINE DERIVATIVES, PREPARATION METHOD THEREFOR AND MEDICINAL USE THEREOF | SHANGHAI HAIYAN PHARMACEUTICAL TECH CO LTD (US) | 2020-08-26 | — | — | EP | disclosed |
| EP-3144292-A1 | 2,3,4,6-TETRA-SUBSTITUTED BENZENE-1,5-DIAMINE DERIVATIVES, PREPARATION METHOD THEREFOR AND MEDICINAL USE THEREOF | SHANGHAI HAIYAN PHARMACEUTICAL TECHNOLOGY CO., LTD (US) | 2017-03-22 | — | — | EP | disclosed |