Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSL | P07711 | 1/20 | 0.53 |
| ▸ | KLK7 | P49862 | 3/20 | 0.52 |
| ▸ | KLK5 | Q9Y337 | 3/20 | 0.52 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | CCKBR | P32239 | 3/20 | 0.48 |
| ▸ | PSMB8 | P28062 | 1/20 | 0.47 |
| ▸ | PSMB9 | P28065 | 1/20 | 0.47 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.47 |
| ▸ | REN | P00797 | 2/20 | 0.47 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.47 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.46 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18659587 | 0.94 | CTSL (0.47) | CTSLKLK7KLK5MAPTCCKBR | |
| SCHEMBL18659589 | 0.93 | KLK7 (0.46) | CTSLKLK7KLK5MAPTCCKBR | |
| SCHEMBL17073778 | 0.90 | CTSL (0.64) | CTSLKLK7KLK5MAPTCCKBR | |
| SCHEMBL18659557 | 0.89 | CTSL (0.55) | CTSLSIRT2 | |
| SCHEMBL18659583 | 0.89 | CTSL (0.51) | CTSLRENSIRT2 | |
| SCHEMBL17073796 | 0.88 | CTSL (0.56) | CTSLSIRT2 | |
| SCHEMBL16869898 | 0.88 | MAPT (0.59) | CTSLKLK7KLK5MAPTCCKBR | |
| SCHEMBL31679023 | 0.88 | CTSL (0.57) | CTSLKLK7KLK5MAPTCCKBR | |
| SCHEMBL17073813 | 0.87 | CTSL (0.52) | CTSLSIRT2 | |
| SCHEMBL17073798 | 0.87 | CTSL (0.52) | CTSLSIRT2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170081363-A1 | PHARMACEUTICALLY RELEVANT AROMATIC-CATIONIC PEPTIDES | STEALTH BIOTHERAPEUTICS CORP (MC) | 2017-03-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170081363-A1 | PHARMACEUTICALLY RELEVANT AROMATIC-CATIONIC PEPTIDES | ADM2, VIP, ANPEP | CTSL 200/4885KLK7 649/4885KLK5 1105/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.