Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 8/20 | 0.79 |
| ▸ | MEN1 | O00255 | 7/20 | 0.79 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.79 |
| ▸ | TUBB4A | P04350 | 7/20 | 0.79 |
| ▸ | TUBB | P07437 | 7/20 | 0.79 |
| ▸ | TUBA3C | P0DPH7 | 7/20 | 0.79 |
| ▸ | TUBA1B | P68363 | 7/20 | 0.79 |
| ▸ | TUBA4A | P68366 | 7/20 | 0.79 |
| ▸ | TUBB4B | P68371 | 7/20 | 0.79 |
| ▸ | TUBB3 | Q13509 | 7/20 | 0.79 |
| ▸ | TUBB2A | Q13885 | 7/20 | 0.79 |
| ▸ | TUBB8 | Q3ZCM7 | 7/20 | 0.79 |
| ▸ | TUBA3E | Q6PEY2 | 7/20 | 0.79 |
| ▸ | TUBA1A | Q71U36 | 7/20 | 0.79 |
| ▸ | TUBA1C | Q9BQE3 | 7/20 | 0.79 |
| ▸ | TUBB6 | Q9BUF5 | 7/20 | 0.79 |
| ▸ | TUBB2B | Q9BVA1 | 7/20 | 0.79 |
| ▸ | TUBB1 | Q9H4B7 | 7/20 | 0.79 |
| ▸ | CYP3A4 | P08684 | 6/20 | 0.79 |
| ▸ | LMNA | P02545 | 6/20 | 0.79 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Vinzolidine SCHEMBL29824738 | 1.00 | MAPT (0.79) | MAPTMEN1KMT2ATUBB4ATUBB | |
| Vinzolidine SCHEMBL4849 | 0.98 | MAPT (0.80) | MAPTMEN1KMT2ATUBB4ATUBB | |
| Vinzolidine SCHEMBL29358211 | 0.98 | MAPT (0.79) | MAPTMEN1KMT2ATUBB4ATUBB | |
| Vinzolidine SCHEMBL10646933 | 0.96 | MAPT (0.75) | MAPTMEN1KMT2ATUBB4ATUBB | |
| SCHEMBL14379965 | 0.89 | MAPT (0.88) | MAPTMEN1KMT2ATUBB4ATUBB | |
| SCHEMBL14498074 | 0.89 | MAPT (0.88) | MAPTMEN1KMT2ATUBB4ATUBB | |
| Vinblastine SCHEMBL17813675 | 0.89 | MAPT (1.00) | MAPTMEN1KMT2ATUBB4ATUBB | |
| Vinblastine SCHEMBL153952 | 0.89 | MAPT (1.00) | MAPTMEN1KMT2ATUBB4ATUBB | |
| Vinblastine SCHEMBL22022258 | 0.89 | MAPT (1.00) | MAPTMEN1KMT2ATUBB4ATUBB | |
| Vinblastine SCHEMBL22450052 | 0.89 | MAPT (1.00) | MAPTMEN1KMT2ATUBB4ATUBB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Appears in 3759 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4524131-A1 | SMALL MOLECULES FOR TREATING CANCER, INHABITING CHEMOKINE ACTIVITY AND/OR INDUCING CELL DEATH | AlonBio Ltd. (IL) | 2025-03-19 | — | — | EP | claimed |
| US-12202803-B2 | Small molecules for treating cancer, inhibiting chemokine activity and/or inducing cell death | ALONBIO LTD. (IL) | 2025-01-21 | — | — | US | claimed |
| US-20240002347-A1 | SMALL MOLECULES FOR TREATING CANCER, INHIBITING CHEMOKINE ACTIVITY AND/OR INDUCING CELL DEATH | ALONBIO LTD. (IL) | 2024-01-04 | — | — | US | claimed |
| EP-2796112-B2 | Degradable implantable medical devices | ELIXIR MEDICAL CORP (US) | 2023-08-09 | — | — | EP | claimed |
| CN-113491690-B | Use of 2-acetylnaphtho [2,3-b ] furan-4, 9-dione for treating cancer | 北京强新生物科技有限公司 | 2023-03-14 | — | — | CN | claimed |
| EP-3441089-B1 | TREATMENT METHODS USING ADENOVIRUS | VASCULAR BIOGENICS LTD (IL) | 2022-12-14 | — | — | EP | claimed |
| WO-2022087375-A1 | NOVEL HETEROCYCLIC COMPOUNDS | SPECTRUM PHARMACEUTICALS, INC. (US) | 2022-04-28 | — | — | WO | claimed |
| WO-2022087371-A1 | NOVEL BICYCLIC COMPOUNDS | SPECTRUM PHARMACEUTICALS, INC. (US) | 2022-04-28 | — | — | WO | claimed |
| CN-113491690-A | Use of 2-acetylnaphtho [2,3-b ] furan-4, 9-dione for treating cancer | 北京强新生物科技有限公司 | 2021-10-12 | — | — | CN | claimed |
| EP-3191114-B1 | OCCIDIOFUNGIN FORMULATIONS AND USES THEREOF | UNIV MISSISSIPPI STATE (US) | 2021-03-03 | — | — | EP | claimed |
| WO-2002085400-A1 | COMPOSITIONS AND METHODS FOR REESTABLISHING GENE TRANSCRIPTION THROUGH INHIBITION OF DNA METHYLATION AND HISTONE DEACETYLASE | SUPERGEN, INC. (US) | 2002-10-31 | — | — | WO | claimed |
| WO-2002067681-A1 | RESTORE CANCER-SUPPRESSING FUNCTIONS TO NEOPLASTIC CELLS THROUGH DNA HYPOMETHYLATION | SUPERGEN, INC. (US) | 2002-09-06 | — | — | WO | claimed |
| US-20020114809-A1 | Restore cancer-suppressing functions to neoplastic cells through DNA hypomethylation | ASTEX PHARMACEUTICALS, INC. | 2002-08-22 | — | — | US | claimed |
| US-20020111362-A1 | Inhibition of abnormal cell proliferation with camptothecin and combinations including the same | SUPERGEN, INC. | 2002-08-15 | — | — | US | claimed |
| WO-2001080843-A2 | INHIBITION OF ABNORMAL CELL PROLIFERATION WITH CAMPTOTHECIN AND COMBINATIONS INCLUDING THE SAME | SUPERGEN, INC. (US) | 2001-11-01 | — | — | WO | claimed |
| EP-0393575-B1 | Neoplasia treatment compositions containing antineoplastic agent and side-effect reducing protective agent | SEARLE & CO (US) | 1994-03-16 | — | — | EP | claimed |
| EP-0393575-A1 | Neoplasia treatment compositions containing antineoplastic agent and side-effect reducing protective agent | G.D. Searle & Co. (US) | 1990-10-24 | — | — | EP | claimed |
| EP-0147152-B1 | IMPROVEMENTS IN OR RELATING TO NOVEL SALTS OF DIMERIC INDOLE-DIHYDROINDOLE ALKALOIDS | ELI LILLY AND COMPANY (US) | 1988-06-29 | — | — | EP | claimed |
| US-4558053-A | Naphthalene-1,5-disulfonate salts of dimeric indole-dihydroindole alkaloids | ELI LILLY AND COMPANY (US) | 1985-12-10 | — | — | US | claimed |
| EP-0147152-A2 | Improvements in or relating to novel salts of dimeric indole-dihydroindole alkaloids | ELI LILLY AND COMPANY (US) | 1985-07-03 | — | — | EP | claimed |